Systemic inflammatory changes and their clinical implications following thoracic cancer surgery

Trauma that follows every surgical procedure triggers an inflammatory response, which in the majority of the cases reflects the associated tissue damage. Tissue regeneration, postoperative outcomes, and systemic antibacterial activity are highly dependent on the initial inflammatory response elicite...

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Published inIndian journal of thoracic and cardiovascular surgery Vol. 38; no. 5; pp. 487 - 496
Main Authors Fornasiero, Massimiliano, Geropoulos, Georgios, Giannis, Dimitrios, Enson, Joshua, Aquilina, Julian, Kumar, Niraj, Bhakhri, Kunal, Panagiotopoulos, Nikolaos
Format Journal Article
LanguageEnglish
Published Singapore Springer Nature Singapore 01.09.2022
Subjects
Cardiac Surgery
Medicine
Medicine & Public Health
Review
Review Article
Surgery
Thoracic Surgery
Vascular Surgery
Robotic surgery
Inflammatory response
Thoracic surgery
Video-assisted thoracoscopic surgery
Systemic inflammation
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Summary:Trauma that follows every surgical procedure triggers an inflammatory response, which in the majority of the cases reflects the associated tissue damage. Tissue regeneration, postoperative outcomes, and systemic antibacterial activity are highly dependent on the initial inflammatory response elicited by surgical trauma. More specifically, in thoracic surgery, systemic cytokine and cellular changes have an impact on several measured postoperative outcomes. Lastly, the introduction of video-assisted and robotic-assisted thoracic surgery has been shown to provide improved postoperative outcomes with altered systemic inflammatory response, when compared to open thoracic surgery. This review outlines the major systemic inflammatory changes observed in thoracic cancer surgery as well as its clinical significance.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ISSN:0970-9134
0973-7723
DOI:10.1007/s12055-021-01301-2