Macrocyclic diarylheptanoids from Garuga pinnata

• Published in: Phytochemistry (Oxford) Vol. 67; no. 24; pp. 2659 - 2662
• Main Authors: Ara, Kulsum, Rahman, A.H.M.M., Hasan, Choudhury M., Iskander, Magdy N., Asakawa, Yoshinori, Quang, Dang N., Rashid, Mohammad A.
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 01.12.2006; Elsevier
• Subjects: aromatic hydrocarbons; Biochemistry & Molecular Biology; Biological and medical sciences; Burseraceae; Burseraceae - chemistry; Chemical constitution; chemical structure; desmethylgarugamblin; diarylheptanoid; Diarylheptanoids; Diarylheptanoids - chemistry; Diarylheptanoids - isolation & purification; didesmethylgaruganin; Fundamental and applied biological sciences. Psychology; Garuga pinnata; heptane; hydroxygaruganin; Life Sciences & Biomedicine; Magnetic Resonance Spectroscopy; medicinal plants; Molecular Structure; Plant Bark - chemistry; Plant Extracts - chemistry; Plant Extracts - isolation & purification; Plant physiology and development; Plant Sciences; Plants, Medicinal - chemistry; Science & Technology; spectral analysis; India; Burseraceae; Diarylheptanoids; Garuga pinnata; diarylheptanoids; Molecular structure; Dicotyledones; Angiospermae; Bark; Isolation; Spermatophyta; Stem; Macrocycle
• ISSN: 0031-9422; 1873-3700
• DOI: 10.1016/j.phytochem.2006.08.013

Three macrocyclic diarylheptanoids, 6′-hydroxygaruganin V ( 1), 9′-desmethylgarugamblin I ( 2) and 1,9′-didesmethylgaruganin III ( 3) were isolated from the petroleum ether and dichloromethane extracts of the stem bark of Garuga pinnata. The structures of these compounds were established by extensive spectroscopic studies, including high field NMR and MS measurements. Three macrocyclic diarylheptanoids, 6′-hydroxygaruganin V ( 1), 9′-desmethylgarugamblin I ( 2) and 1,9′-didesmethylgaruganin III ( 3) were isolated from the petroleum ether and dichloromethane extracts of the stem bark of Garuga pinnata. The structures of these compounds were established by extensive spectroscopic studies, including high field NMR and MS measurements.