New Curvularin-Type Metabolites from the Hybrid Strain ME 0005 Derived from Penicillium Citreo-viride B. IFO 4692 and 6200

Four new curvularin-type metabolites (11-α-methoxycurvularin, 11-β-methoxy curvularin, 11,12-dihydroxycurvularin, and 12-hydroxy-10, 11-trans-dehydrocurvularin) have been isolated from the mycelium of the hybrid strain ME 0005 derived from Penicillium citreo-viride B. IFO 4692 and 6200. And β-hydrox...

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Bibliographic Details
Published inBulletin of the Chemical Society of Japan Vol. 64; no. 3; pp. 1048 - 1050
Main Authors Lai, Sheng, Shizuri, Yoshikazu, Yamamura, Shosuke, Kawai, Kazuaki, Furukawa, Hideyuki
Format Journal Article
LanguageEnglish
Published Tokyo The Chemical Society of Japan 01.03.1991
Chemical Society of Japan
Subjects
Analytical, structural and metabolic biochemistry
Aromatic and heterocyclic compounds
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Heterocyclic compounds, pigments
Other biological molecules
Molecular structure
Bicyclic compound
Isolation
Lactone
Aromatic compound
Oxygen heterocycle
NMR spectrum
Diphenols
Macrocycle
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Summary:Four new curvularin-type metabolites (11-α-methoxycurvularin, 11-β-methoxy curvularin, 11,12-dihydroxycurvularin, and 12-hydroxy-10, 11-trans-dehydrocurvularin) have been isolated from the mycelium of the hybrid strain ME 0005 derived from Penicillium citreo-viride B. IFO 4692 and 6200. And β-hydroxycurvularin, the biologically active principle from Alternaria tomato, was identified as 11-β-hydroxycurvularin.
ISSN:0009-2673
1348-0634
DOI:10.1246/bcsj.64.1048