Serum hyperviscosity syndrome responding to therapeutic plasmapheresis in a patient with primary Sjögren's syndrome

• Published in: Journal of clinical apheresis Vol. 17; no. 1; pp. 44 - 46
• Main Authors: Simón, J. Abraham, Lazo-Langner, Alejandro, Duarte-Rojo, Andrés, Velázquez-González, Antonio, Sánchez-Guerrero, Sergio A., Sánchez-Guerrero, Jorge
• Format: Journal Article
• Language: English
• Published: New York Wiley Subscription Services, Inc., A Wiley Company 2002; Wiley-Liss
• Subjects: Adult; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Autoantibodies - blood; Autoimmune Diseases - blood; Biological and medical sciences; Blood Viscosity; Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis; Female; Humans; hyperviscosity; Medical sciences; Plasma Exchange; plasmapheresis; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; Sjogren's Syndrome - blood; Sjögren's syndrome; Syndrome; therapeutic plasma exchange; Transfusions. Complications. Transfusion reactions. Cell and gene therapy; Human; Immunopathology; Stomatology; Treatment efficiency; Autoimmune disease; Sjögren syndrome; Plasmapheresis; Case study; Plasma exchange; Eye disease; Hyperviscosity syndrome; Systemic disease; Adult; Complication; Female
• ISSN: 0733-2459; 1098-1101
• DOI: 10.1002/jca.10018

Hyperviscosity syndrome is a disorder first described in patients with Waldenström's macroglobulinemia and is not commonly seen in rheumatic diseases. Its association with Sjögren's syndrome is very rare and it has been reported in very few patients. We report the case of a patient with primary Sjögren's syndrome presenting as hyperviscosity syndrome who was successfully treated with therapeutic plasma exchange. J. Clin. Apheresis 17:44–46, 2002.