Effects of dietary supplementation with Clostridium butyricum on the growth performance and humoral immune response in Miichthys miiuy

• Published in: Journal of Zhejiang University. B. Science Vol. 7; no. 7; pp. 596 - 602
• Main Authors: Song, Zeng-fu, Wu, Tian-xing, Cai, Li-sheng, Zhang, Li-jing, Zheng, Xiao-dong
• Format: Journal Article
• Language: English
• Published: China Springer Nature B.V 01.07.2006; Zhejiang University Press
• Series: Science Letters
• Subjects: Acid phosphatase; Animal Feed - microbiology; Animals; Antibody Formation - physiology; Aquaculture; Biotechnological Engineering; Clostridium butyricum; Clostridium butyricum - immunology; Dietary Supplements - microbiology; Fishes - growth & development; Fishes - immunology; Hogs; Immune system; Probiotics - administration & dosage; 体液免疫响应; 生长性能
• ISSN: 1673-1581; 1862-1783
• DOI: 10.1631/jzus.2006.B0596

The effects of dietary supplementation with Clostridium butyricum on growth performance and humoral immune response in Miichthys miiuy were evaluated. One hundred and fifty Miichthys miiuy weighing approximately 200-260 g were divided into five groups and reared in 15 tanks with closed circuiting culture system. The animals were fed 5 diets： basal diet only （control） or supplemented of the basal diet with C. butyricum at doses of 10^3 （CB1）, 10^5 （CB2）, 10^7 （CB3） or 10^9 （CB4） CFU/g. Compared with the control, the serum phenoloxidase activity was significantly increased by the supplementation （P〈0.05）, acid phosphatases activity was increased significantly （P〈0.05） at the doses of 10^9 CFU/g. Serum lysozyme activity peaked at dose of 10^7 CFU/g and in the skin mucus at dose of 10^9 CFU/g. Immunoglobulin M level in the serum and skin mucus was increased except at dose of 10^3 CFU/g （P〈0.05）. The growth at the dose of 10^9 CFU/g was higher than that of the control （P〈0.05）. It is concluded that supplementation of C. butyricum can mediate the humoral immune responses and improve the growth performance in Miichthys miiuy.