Erratum: “Low-Level Environmental Lead Exposure and Children’s Intellectual Function: An International Pooled Analysis”

• Published in: Environmental health perspectives Vol. 127; no. 9; p. 99001
• Main Authors: Lanphear, Bruce P, Hornung, Richard, Khoury, Jane, Yolton, Kimberly, Baghurst, Peter, Bellinger, David C, Canfield, Richard L, Dietrich, Kim N, Bornschein, Robert, Greene, Tom, Rothenberg, Stephen J, Needleman, Herbert L, Schnaas, Lourdes, Wasserman, Gail, Graziano, Joseph, Roberts, Russell
• Format: Journal Article
• Language: English
• Published: Research Triangle Park National Institute of Environmental Health Sciences 01.09.2019; Environmental Health Perspectives
• Subjects: Blood levels; Childhood; Cognitive ability; Erratum; Lead; Australia; Massachusetts
• ISSN: 0091-6765; 1552-9924
• DOI: 10.1289/EHP5685

[...]we reanalyzed the data using full scale IQ data and corrected blood lead levels for the Boston cohort and provide the corrected data and results in the revised text. Other studies were limited because they involved children whose blood lead levels may have exceeded 10   μg /dL at some point in their lifetime or because important covariates, such as maternal IQ scores, were not always available (Fulton et al. 1987; Lanphear et al. 2000; Schwartz 1994, Schwartz and Otto 1991; Walkowiak et al. 1998). Because of the policy implications of this research, it is critical to estimate with greater precision the exposure-response relationship at blood lead levels < 10   μg /dL . The shape of the exposure-response relationship was determined to be nonlinear insofar as the quadratic and cubic terms for concurrent blood lead were statistically significant ( p < 0.001 and p = 0.003 , respectively). Because the restrictive cubic spline indicated that a log-linear model provided a good fit to the data, we used the log of concurrent blood lead in all subsequent analyses of the pooled data (Figure 1). [...]the results of this pooled analysis underscore the increasing importance of primary prevention as the consequences of lower blood lead concentrations are recognized.