Torsades de pointes – a report of a case induced by caesium taken as a complementary medicine, and the literature review

• Published in: Journal of clinical pharmacy and therapeutics Vol. 38; no. 3; pp. 254 - 257
• Main Authors: Young, F., Bolt, J.
• Format: Journal Article
• Language: English
• Published: Oxford Blackwell 01.06.2013; Hindawi Limited
• Subjects: Biological and medical sciences; caesium; Carbonates - adverse effects; Carbonates - therapeutic use; Cardiac dysrhythmias; Cardiology. Vascular system; Cesium - adverse effects; Cesium - therapeutic use; Complementary Therapies - adverse effects; Female; Heart; Humans; Medical sciences; Middle Aged; Pharmacology. Drug treatments; torsades de pointes; Torsades de Pointes - chemically induced; Case study; caesium; Arrhythmia; Heart disease; Alternative medicine; Torsades de pointes; Cardiovascular disease; Excitability disorder; Bibliographic review
• ISSN: 0269-4727; 1365-2710
• DOI: 10.1111/jcpt.12053

Summary What is known and objective Complementary medicines are commonly used by many patients. Caesium, a complementary therapy said to be of benefit for cancer treatment, has been associated with cardiac arrhythmias in the literature. We report a case of caesium‐induced torsades de pointes and provide an evidence review. Case summary A 46‐year‐old woman with syncope experienced torsades de pointes and cardiac arrest. Upon admission her QTc was 620 ms. The patient had taken caesium carbonate 10 g daily for 1 month prior to admission. The patient was successfully resuscitated and discharged home after 35 days in hospital. What is new and conclusion Ten cases of caesium‐induced cardiac arrhythmias have previously been reported in the literature. Treatment strategies differed significantly among the cases. However, all patients recovered from the event. Complementary and alternative medicines should not be overlooked as a potential cause of serious adverse events.