Liquid Viruses by Nanoscale Engineering of Capsid Surfaces

Surface engineering of plant virus capsids via cationization (1) and stoichiometric coupling of a polymer surfactant coronal layer (2) produces a highly concentrated, solvent‐free liquid virus at 28 °C. These ionic bionanoconstructs are viscoelastic, retain plant infectivity and can be dispersed in...

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Published inAdvanced materials (Weinheim) Vol. 24; no. 33; pp. 4557 - 4563
Main Authors Patil, Avinash J., McGrath, Nina, Barclay, J. Elaine, Evans, David J., Cölfen, Helmut, Manners, Ian, Perriman, Adam W., Mann, Stephen
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag 28.08.2012
WILEY‐VCH Verlag
Subjects
Capsid - chemistry
Comovirus - chemistry
Comovirus - physiology
Engineering - methods
Fabaceae - virology
Models, Molecular
Nanotechnology - methods
Optical Imaging
Protein Conformation
Surface Properties
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Summary:Surface engineering of plant virus capsids via cationization (1) and stoichiometric coupling of a polymer surfactant coronal layer (2) produces a highly concentrated, solvent‐free liquid virus at 28 °C. These ionic bionanoconstructs are viscoelastic, retain plant infectivity and can be dispersed in a range of organic solvents for aerosol delivery.
Bibliography:ark:/67375/WNG-KQF0JMG6-Q
ArticleID:ADMA201201032
istex:EE0F95A86E31A51980BCE9AA55802CB7F02AF04C
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201201032