Planned neck dissection for advanced primary head and neck malignancy treated with organ preservation therapy: Disease control and survival outcomes
Background The role of planned neck dissection after organ preservation therapy with radiotherapy or chemotherapy/radiotherapy for advanced head and neck cancers presenting with clinically positive neck disease is still being elucidated. The aim of this study is to review the outcomes of such patien...
Saved in:
Published in | Head & neck Vol. 23; no. 2; pp. 73 - 79 |
---|---|
Main Authors | , , , , , |
Format | Journal Article Conference Proceeding |
Language | English |
Published |
New York
John Wiley & Sons, Inc
01.02.2001
John Wiley & Sons |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Background
The role of planned neck dissection after organ preservation therapy with radiotherapy or chemotherapy/radiotherapy for advanced head and neck cancers presenting with clinically positive neck disease is still being elucidated. The aim of this study is to review the outcomes of such patients treated by organ preservation therapy at our institution.
Methods
A retrospective chart review of 33 patients who underwent planned neck dissections after organ preservation therapy for advanced primary head and neck malignancy. Endpoints measured were disease‐free survival and local, regional, and distant control.
Setting
Tertiary metropolitan medical center.
Results
Two‐year actuarial disease‐free survival was 61%, and neck control was 92%, with only two failures in the neck. The use of neoadjuvant chemotherapy and total dose of radiotherapy did not correlate with neck control or disease‐free survival. The presence of pathologically positive nodal disease at the time of neck dissection did not correlate with recurrent neck disease, but was a predictor of local recurrence (p = .0086).
Conclusions
Our data suggest that for patients undergoing planned neck dissection after organ preservation therapy, neck control is obtained in almost all cases. The presence of pathologically positive nodal disease at the time of surgery may have implications for the incidence of local recurrence. © 2001 John Wiley & Sons, Inc., Head Neck 23: 73–79, 2001. |
---|---|
AbstractList | BACKGROUNDThe role of planned neck dissection after organ preservation therapy with radiotherapy or chemotherapy/radiotherapy for advanced head and neck cancers presenting with clinically positive neck disease is still being elucidated. The aim of this study is to review the outcomes of such patients treated by organ preservation therapy at our institution.METHODSA retrospective chart review of 33 patients who underwent planned neck dissections after organ preservation therapy for advanced primary head and neck malignancy. Endpoints measured were disease-free survival and local, regional, and distant control.SETTINGTertiary metropolitan medical center.RESULTSTwo-year actuarial disease-free survival was 61%, and neck control was 92%, with only two failures in the neck. The use of neoadjuvant chemotherapy and total dose of radiotherapy did not correlate with neck control or disease-free survival. The presence of pathologically positive nodal disease at the time of neck dissection did not correlate with recurrent neck disease, but was a predictor of local recurrence (p = .0086).CONCLUSIONSOur data suggest that for patients undergoing planned neck dissection after organ preservation therapy, neck control is obtained in almost all cases. The presence of pathologically positive nodal disease at the time of surgery may have implications for the incidence of local recurrence. Background The role of planned neck dissection after organ preservation therapy with radiotherapy or chemotherapy/radiotherapy for advanced head and neck cancers presenting with clinically positive neck disease is still being elucidated. The aim of this study is to review the outcomes of such patients treated by organ preservation therapy at our institution. Methods A retrospective chart review of 33 patients who underwent planned neck dissections after organ preservation therapy for advanced primary head and neck malignancy. Endpoints measured were disease‐free survival and local, regional, and distant control. Setting Tertiary metropolitan medical center. Results Two‐year actuarial disease‐free survival was 61%, and neck control was 92%, with only two failures in the neck. The use of neoadjuvant chemotherapy and total dose of radiotherapy did not correlate with neck control or disease‐free survival. The presence of pathologically positive nodal disease at the time of neck dissection did not correlate with recurrent neck disease, but was a predictor of local recurrence (p = .0086). Conclusions Our data suggest that for patients undergoing planned neck dissection after organ preservation therapy, neck control is obtained in almost all cases. The presence of pathologically positive nodal disease at the time of surgery may have implications for the incidence of local recurrence. © 2001 John Wiley & Sons, Inc., Head Neck 23: 73–79, 2001. The role of planned neck dissection after organ preservation therapy with radiotherapy or chemotherapy/radiotherapy for advanced head and neck cancers presenting with clinically positive neck disease is still being elucidated. The aim of this study is to review the outcomes of such patients treated by organ preservation therapy at our institution. A retrospective chart review of 33 patients who underwent planned neck dissections after organ preservation therapy for advanced primary head and neck malignancy. Endpoints measured were disease-free survival and local, regional, and distant control. Tertiary metropolitan medical center. Two-year actuarial disease-free survival was 61%, and neck control was 92%, with only two failures in the neck. The use of neoadjuvant chemotherapy and total dose of radiotherapy did not correlate with neck control or disease-free survival. The presence of pathologically positive nodal disease at the time of neck dissection did not correlate with recurrent neck disease, but was a predictor of local recurrence (p = .0086). Our data suggest that for patients undergoing planned neck dissection after organ preservation therapy, neck control is obtained in almost all cases. The presence of pathologically positive nodal disease at the time of surgery may have implications for the incidence of local recurrence. |
Author | Newkirk, Kenneth A. Picken, Catherine A. Sessions, Roy B. Cullen, Kevin J. Harter, K. WIlliam Davidson, Bruce J. |
Author_xml | – sequence: 1 givenname: Kenneth A. surname: Newkirk fullname: Newkirk, Kenneth A. organization: Department of Otolaryngology-Head and Neck Surgery, Georgetown University Medical Center, 3800 Reservoir Road, Washington, DC 20007 – sequence: 2 givenname: Kevin J. surname: Cullen fullname: Cullen, Kevin J. organization: Division of Hematology/Oncology, Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC – sequence: 3 givenname: K. WIlliam surname: Harter fullname: Harter, K. WIlliam organization: Department of Radiation Oncology, Georgetown University Medical Center, Washington, DC – sequence: 4 givenname: Catherine A. surname: Picken fullname: Picken, Catherine A. organization: Department of Otolaryngology-Head and Neck Surgery, Georgetown University Medical Center, 3800 Reservoir Road, Washington, DC 20007 – sequence: 5 givenname: Roy B. surname: Sessions fullname: Sessions, Roy B. organization: Department of Otolaryngology-Head and Neck Surgery, Beth Israel Medical Center, New York, New York – sequence: 6 givenname: Bruce J. surname: Davidson fullname: Davidson, Bruce J. email: otorhino@pol.net organization: Department of Otolaryngology-Head and Neck Surgery, Georgetown University Medical Center, 3800 Reservoir Road, Washington, DC 20007 |
BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=852724$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/11303636$$D View this record in MEDLINE/PubMed |
BookMark | eNqNkd1uEzEQhVeoiP7AKyBLSAguNvhv422KkEpS2oqqyUUQEjfWxDvbmG7sYG9S8h48ME6zhBsuuPLI883x-Jzj7MB5h1lWMtpjlPJ3jJ6qnAqp3nBKGeVvuRjw90oMBufXo_zqYpQo9kH0aG84PuN5_0l2tB852NZS5IIqeZgdx_idUir6kj_LDhkTqRT9o-zXpAHnsCIOzT2pbIxoWusdqX0gUK3BmdRcBruAsCFzhIqA6-gFNPbOJWJD2oDQJvDBtnPiwx24NIMRwxoe1do5BlhuBmRkI0JEYrxrg28exeIqrO0aGuJXrfELjM-zpzU0EV9050n25dPFdHiV34wvr4fnN7mRXLAcRDFjJUcJQhSlMlCXRhZVpSTjopRqxutTZmYcCskEw5k0BVdlQQWYxKbzJHu9010G_2OFsdULGw02yRL0q6iVokWykyVwsgNN8DEGrHXniGZUb5PSW9v11na9S0pzoblWQuuUlO6S0kJTPRynRj9JvuzeXs0WWP0V7KJJwKsOgGigqUMy2sY9V6a_cJmo6Y56sA1u_n-tf2_15yrJ5jtZG1v8uZeFcK_7SqhCf7291B8n324_Twqqp-I3McHLVw |
Cites_doi | 10.1288/00005537-197606000-00009 10.1177/000348949910800204 10.1001/archotol.125.2.142 10.1148/radiology.184.1.1609090 10.1288/00005537-199208000-00015 10.1001/archotol.124.9.951 10.1001/archotol.1997.01900020023003 10.1001/archotol.125.4.401 10.1016/S0002-9610(98)00240-2 10.1002/(SICI)1097-0347(199710)19:7<559::AID-HED1>3.0.CO;2-6 10.1016/S0360-3016(97)00148-X 10.1001/archotol.1995.01890090018003 10.1001/archotol.124.4.401 10.1016/S0002-9610(05)80734-2 10.1056/NEJM199106133242402 10.1002/(SICI)1520-6823(1998)6:1<52::AID-ROI6>3.0.CO;2-H |
ContentType | Journal Article Conference Proceeding |
Copyright | Copyright © 2001 John Wiley & Sons, Inc. 2001 INIST-CNRS |
Copyright_xml | – notice: Copyright © 2001 John Wiley & Sons, Inc. – notice: 2001 INIST-CNRS |
DBID | BSCLL IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
DOI | 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6 |
DatabaseName | Istex Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE - Academic MEDLINE |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
EISSN | 1097-0347 |
EndPage | 79 |
ExternalDocumentID | 10_1002_1097_0347_200102_23_2_73__AID_HED1001_3_0_CO_2_6 11303636 852724 HED1001 ark_67375_WNG_BPZNKP50_T |
Genre | article Journal Article |
GroupedDBID | --- .3N .55 .GA .Y3 05W 0R~ 10A 1L6 1OB 1OC 1ZS 31~ 33P 36B 3O- 3SF 3WU 4.4 4ZD 50Y 50Z 51W 51X 52M 52N 52O 52P 52R 52S 52T 52U 52V 52W 52X 53G 5GY 5VS 66C 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A01 A03 AAESR AAEVG AAHHS AANLZ AAONW AASGY AAVGM AAXRX AAZKR ABCQN ABCUV ABEML ABHUG ABIJN ABQWH ABXGK ACAHQ ACBWZ ACCFJ ACCZN ACGFS ACGOF ACMXC ACPOU ACPRK ACSCC ACXBN ACXME ACXQS ADAWD ADBBV ADBTR ADDAD ADEOM ADIZJ ADKYN ADMGS ADOZA ADZMN ADZOD AEEZP AEIGN AEIMD AEQDE AEQTP AEUQT AEUYR AFBPY AFFPM AFGKR AFPWT AFVGU AFZJQ AGJLS AHBTC AHMBA AIACR AIURR AIWBW AJBDE ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN AMBMR AMYDB ASPBG ATUGU AVWKF AZBYB AZFZN AZVAB BAFTC BDRZF BFHJK BHBCM BROTX BRXPI BSCLL BY8 C45 CS3 D-6 D-7 D-E D-F DCZOG DPXWK DR2 DRFUL DRMAN DRSTM DUUFO EBD EBS EJD EMB EMOBN F00 F01 F04 F5P FEDTE G-S G.N GNP GODZA H.X HBH HF~ HHY HHZ HVGLF HZ~ IX1 J0M JPC KBYEO KQQ LATKE LAW LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES M6P MEWTI MK4 MRFUL MRMAN MRSTM MSFUL MSMAN MSSTM MXFUL MXMAN MXSTM N04 N05 N9A NF~ NNB O66 O9- OVD P2W P2X P2Z P4B P4D PALCI PQQKQ Q.N Q11 QB0 QRW R.K RIWAO ROL RWI RX1 RYL SAMSI SUPJJ SV3 TEORI UB1 V2E W8V W99 WBKPD WH7 WHWMO WIH WIJ WIK WJL WOHZO WQJ WRC WUP WVDHM WWO WXI WXSBR X7M XG1 XPP XV2 ZGI ZXP ZZTAW ~IA ~WT AITYG HGLYW OIG AAUGY IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
ID | FETCH-LOGICAL-c4231-a35b182e4a33587caf8c45dd74123847b2f91cb2a54131eb4c5278503accaf503 |
IEDL.DBID | DR2 |
ISSN | 1043-3074 |
IngestDate | Sat Aug 17 03:11:59 EDT 2024 Fri Aug 23 02:27:56 EDT 2024 Sat Sep 28 07:36:29 EDT 2024 Sun Oct 22 16:08:34 EDT 2023 Sat Aug 24 00:40:45 EDT 2024 Wed Jan 17 05:01:57 EST 2024 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 2 |
Keywords | Local dissemination Relapse Malignant lymphadenopathy Metastasis Chemoradiotherapy Incidence Conservative surgery Organ preservation Surgery Head and neck ENT disease Adult Lymphatic dissemination Neck Dissection Survival curve Blood dissemination Human Treatment efficiency Malignant tumor Radiotherapy Treatment Second cancer Combined treatment Technique Predictive factor Bibliographic review |
Language | English |
License | CC BY 4.0 |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c4231-a35b182e4a33587caf8c45dd74123847b2f91cb2a54131eb4c5278503accaf503 |
Notes | ark:/67375/WNG-BPZNKP50-T ArticleID:HED1001 istex:EF84BDD7049F51257C46E560B48F145379F1D014 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
PMID | 11303636 |
PQID | 77050971 |
PQPubID | 23479 |
PageCount | 7 |
ParticipantIDs | proquest_miscellaneous_77050971 crossref_primary_10_1002_1097_0347_200102_23_2_73__AID_HED1001_3_0_CO_2_6 pubmed_primary_11303636 pascalfrancis_primary_852724 wiley_primary_10_1002_1097_0347_200102_23_2_73_AID_HED1001_3_0_CO_2_6_HED1001 istex_primary_ark_67375_WNG_BPZNKP50_T |
PublicationCentury | 2000 |
PublicationDate | February 2001 |
PublicationDateYYYYMMDD | 2001-02-01 |
PublicationDate_xml | – month: 02 year: 2001 text: February 2001 |
PublicationDecade | 2000 |
PublicationPlace | New York |
PublicationPlace_xml | – name: New York – name: New York, NY – name: United States |
PublicationTitle | Head & neck |
PublicationTitleAlternate | Head Neck |
PublicationYear | 2001 |
Publisher | John Wiley & Sons, Inc John Wiley & Sons |
Publisher_xml | – name: John Wiley & Sons, Inc – name: John Wiley & Sons |
References | Manni JJ, Terhaard CH, deBoer MF, et al. Prognostic factors for survival in patients with T3 laryngeal carcinoma. Am J Surg 1992;164:682-687. Lavertu P, Adelstein DJ, Saxton JP, et al. Aggressive concurrent chemoradiotherapy for squamous cell head and neck cancer. Arch Otolaryngol Head Neck Surg 1999;125:142-148. Wolf GT, Fisher SG. Effectiveness of salvage neck dissection for advanced regional metastases when induction chemotherapy and radiation are used for organ preservation. Laryngoscope 1992;19(7):934-939. Lavertu P, Adelstein DJ, Saxton JP, et al. Management of the neck in a randomized trial comparing concurrent chemotherapy and radiotherapy with radiotherapy alone in resectable stage III and IV squamous cell head and neck cancer. Head Neck 1997;4:559-566. Sessions DG. Surgical pathology of cancer of the larynx and hypopharynx. Laryngoscope 1976;86:814-839. Dagum P, Pinto HA, Newman JP, et al. Management of the clinically positive neck in organ preservation for advanced head and neck cancer. Am J Surg 1998;176:448-452. Hoffman HT, Karnell LH, Funk GF, Robinson RA, Menck HR. The national cancer database report on cancer of the head and neck. Arch Otolaryngol Head Neck Surg 1998;124:951-962. Davidson BJ, Newkirk KA, Harter W, Picken CA, Cullen KJ, Sessions RB. Complications from planned neck dissections. Arch Otolaryngol Head Neck Surg 1999;125:401-405. Pinsolle J, Pinsolle V, Majoufre C, Duroux S, Demeaux H, Siberchicot F. Prognostic value of histologic findings in neck dissections for squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 1997;123:145-148. Lee HJ, Zelefsky MJ, Kraus DH, et al. Long term regional control after radiation therapy and neck dissection for base of tongue carcinoma. Int J Rad Oncol Biol Phys 1997;38(5):995-1000. Lavertu P, Bonafede JP, Adelstein DJ, et al. Comparison of surgical complications after organ preservation therapy in patients with Stage III and IV squamous cell head and neck cancer. Arch Otolaryngol Head Neck Surg 1998;124:401-406. Koch WM, Lee DJ, Eisle DW, et al. Chemoradiotherapy for organ preservation in oral and pharyngeal carcinoma. Arch Otolaryngol Head Neck Surg 1995;121:974-980. Harrison LB, Zelefsky M, Sessions RB, et al. Base of tongue cancer treated with external beam irradiation plus brachytherapy: Oncologic and functional outcome. Radiology 1992;184:267-270. Wang SJ, Wang MB, Calcaterra TC. Radiotherapy followed by neck dissection for small head and neck cancers with advanced cervical metastasis. Ann Otol Rhinol Laryngol 1999;108:128-132. Johnson CR, Silverman LN, Clay LB, Schmidt-Ulrich R. Radiotherapeutic management of bulky cervical lymphadenopathy in squamous cell carcinoma of the head and neck: is postradiotherapy neck dissection necessary?. Radiat Oncol Invest 1998;6(1):52-57. Department of Veteran Affairs Laryngeal Cancer Study Group. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. N Engl J Med 1991;324:1685-1690. 1976; 86 1992; 184 1992; 164 1997; 123 1992; 19 1997; 38 1999; 125 1998; 6 1998; 176 1995; 121 1998; 124 1991; 324 1997; 4 1999; 108 Lavertu (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB3) 1999; 125 Lavertu (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB6) 1998; 124 Wolf (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB4) 1992; 19 Lavertu (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB5) 1997; 4 Wang (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB9) 1999; 108 Hoffman (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB12) 1998; 124 Davidson (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB7) 1999; 125 (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB1) 1991; 324 Sessions (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB15) 1976; 86 Dagum (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB10) 1998; 176 Koch (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB11) 1995; 121 Lee (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB13) 1997; 38 Johnson (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB8) 1998; 6 Pinsolle (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB16) 1997; 123 Harrison (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB2) 1992; 184 Manni (10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB14) 1992; 164 |
References_xml | – volume: 108 start-page: 128 year: 1999 end-page: 132 article-title: Radiotherapy followed by neck dissection for small head and neck cancers with advanced cervical metastasis publication-title: Ann Otol Rhinol Laryngol – volume: 324 start-page: 1685 year: 1991 end-page: 1690 article-title: Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer publication-title: N Engl J Med – volume: 38 start-page: 995 issue: 5 year: 1997 end-page: 1000 article-title: Long term regional control after radiation therapy and neck dissection for base of tongue carcinoma publication-title: Int J Rad Oncol Biol Phys – volume: 19 start-page: 934 issue: 7 year: 1992 end-page: 939 article-title: Effectiveness of salvage neck dissection for advanced regional metastases when induction chemotherapy and radiation are used for organ preservation publication-title: Laryngoscope – volume: 4 start-page: 559 year: 1997 end-page: 566 article-title: Management of the neck in a randomized trial comparing concurrent chemotherapy and radiotherapy with radiotherapy alone in resectable stage III and IV squamous cell head and neck cancer publication-title: Head Neck – volume: 86 start-page: 814 year: 1976 end-page: 839 article-title: Surgical pathology of cancer of the larynx and hypopharynx publication-title: Laryngoscope – volume: 176 start-page: 448 year: 1998 end-page: 452 article-title: Management of the clinically positive neck in organ preservation for advanced head and neck cancer publication-title: Am J Surg – volume: 121 start-page: 974 year: 1995 end-page: 980 article-title: Chemoradiotherapy for organ preservation in oral and pharyngeal carcinoma publication-title: Arch Otolaryngol Head Neck Surg – volume: 124 start-page: 951 year: 1998 end-page: 962 article-title: The national cancer database report on cancer of the head and neck publication-title: Arch Otolaryngol Head Neck Surg – volume: 184 start-page: 267 year: 1992 end-page: 270 article-title: Base of tongue cancer treated with external beam irradiation plus brachytherapy: Oncologic and functional outcome publication-title: Radiology – volume: 125 start-page: 142 year: 1999 end-page: 148 article-title: Aggressive concurrent chemoradiotherapy for squamous cell head and neck cancer publication-title: Arch Otolaryngol Head Neck Surg – volume: 123 start-page: 145 year: 1997 end-page: 148 article-title: Prognostic value of histologic findings in neck dissections for squamous cell carcinoma publication-title: Arch Otolaryngol Head Neck Surg – volume: 125 start-page: 401 year: 1999 end-page: 405 article-title: Complications from planned neck dissections publication-title: Arch Otolaryngol Head Neck Surg – volume: 6 start-page: 52 issue: 1 year: 1998 end-page: 57 article-title: Radiotherapeutic management of bulky cervical lymphadenopathy in squamous cell carcinoma of the head and neck: is postradiotherapy neck dissection necessary? publication-title: Radiat Oncol Invest – volume: 124 start-page: 401 year: 1998 end-page: 406 article-title: Comparison of surgical complications after organ preservation therapy in patients with Stage III and IV squamous cell head and neck cancer publication-title: Arch Otolaryngol Head Neck Surg – volume: 164 start-page: 682 year: 1992 end-page: 687 article-title: Prognostic factors for survival in patients with T3 laryngeal carcinoma publication-title: Am J Surg – volume: 86 start-page: 814 year: 1976 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB15 publication-title: Laryngoscope doi: 10.1288/00005537-197606000-00009 contributor: fullname: Sessions – volume: 108 start-page: 128 year: 1999 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB9 publication-title: Ann Otol Rhinol Laryngol doi: 10.1177/000348949910800204 contributor: fullname: Wang – volume: 125 start-page: 142 year: 1999 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB3 publication-title: Arch Otolaryngol Head Neck Surg doi: 10.1001/archotol.125.2.142 contributor: fullname: Lavertu – volume: 184 start-page: 267 year: 1992 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB2 publication-title: Radiology doi: 10.1148/radiology.184.1.1609090 contributor: fullname: Harrison – volume: 19 start-page: 934 year: 1992 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB4 publication-title: Laryngoscope doi: 10.1288/00005537-199208000-00015 contributor: fullname: Wolf – volume: 124 start-page: 951 year: 1998 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB12 publication-title: Arch Otolaryngol Head Neck Surg doi: 10.1001/archotol.124.9.951 contributor: fullname: Hoffman – volume: 123 start-page: 145 year: 1997 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB16 publication-title: Arch Otolaryngol Head Neck Surg doi: 10.1001/archotol.1997.01900020023003 contributor: fullname: Pinsolle – volume: 125 start-page: 401 year: 1999 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB7 publication-title: Arch Otolaryngol Head Neck Surg doi: 10.1001/archotol.125.4.401 contributor: fullname: Davidson – volume: 176 start-page: 448 year: 1998 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB10 publication-title: Am J Surg doi: 10.1016/S0002-9610(98)00240-2 contributor: fullname: Dagum – volume: 4 start-page: 559 year: 1997 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB5 publication-title: Head Neck doi: 10.1002/(SICI)1097-0347(199710)19:7<559::AID-HED1>3.0.CO;2-6 contributor: fullname: Lavertu – volume: 38 start-page: 995 year: 1997 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB13 publication-title: Int J Rad Oncol Biol Phys doi: 10.1016/S0360-3016(97)00148-X contributor: fullname: Lee – volume: 121 start-page: 974 year: 1995 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB11 publication-title: Arch Otolaryngol Head Neck Surg doi: 10.1001/archotol.1995.01890090018003 contributor: fullname: Koch – volume: 124 start-page: 401 year: 1998 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB6 publication-title: Arch Otolaryngol Head Neck Surg doi: 10.1001/archotol.124.4.401 contributor: fullname: Lavertu – volume: 164 start-page: 682 year: 1992 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB14 publication-title: Am J Surg doi: 10.1016/S0002-9610(05)80734-2 contributor: fullname: Manni – volume: 324 start-page: 1685 year: 1991 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB1 publication-title: N Engl J Med doi: 10.1056/NEJM199106133242402 – volume: 6 start-page: 52 year: 1998 ident: 10.1002/1097-0347(200102)23:2<73::AID-HED1001>3.0.CO;2-6-BIB8 publication-title: Radiat Oncol Invest doi: 10.1002/(SICI)1520-6823(1998)6:1<52::AID-ROI6>3.0.CO;2-H contributor: fullname: Johnson |
SSID | ssj0003642 |
Score | 1.8072397 |
Snippet | Background
The role of planned neck dissection after organ preservation therapy with radiotherapy or chemotherapy/radiotherapy for advanced head and neck... The role of planned neck dissection after organ preservation therapy with radiotherapy or chemotherapy/radiotherapy for advanced head and neck cancers... BACKGROUNDThe role of planned neck dissection after organ preservation therapy with radiotherapy or chemotherapy/radiotherapy for advanced head and neck... |
SourceID | proquest crossref pubmed pascalfrancis wiley istex |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 73 |
SubjectTerms | Biological and medical sciences Combined Modality Therapy Disease-Free Survival Female head and neck cancer Head and Neck Neoplasms - mortality Head and Neck Neoplasms - therapy Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics Humans Male Medical sciences Middle Aged Neck Dissection organ preservation therapy Otorhinolaryngology (head neck, general aspects and miscellaneous) Otorhinolaryngology. Stomatology Retrospective Studies Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the upper aerodigestive tract Treatment Outcome Tumors |
Title | Planned neck dissection for advanced primary head and neck malignancy treated with organ preservation therapy: Disease control and survival outcomes |
URI | https://api.istex.fr/ark:/67375/WNG-BPZNKP50-T/fulltext.pdf https://onlinelibrary.wiley.com/doi/abs/10.1002%2F1097-0347%28200102%2923%3A2%3C73%3A%3AAID-HED1001%3E3.0.CO%3B2-6 https://www.ncbi.nlm.nih.gov/pubmed/11303636 https://search.proquest.com/docview/77050971 |
Volume | 23 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwvV1Nb9MwGLamISEufIivwAAfGIJDusQfcVYQ0tZ2dKB1E9q0iYtlOw6HihQ1jcT4G_CDeW0nLUU7cEBIVVo1jt_Yfm0_th8_Rug54aXmbqIqzTiPWbmr49zmcAFoD2gD3CZ3G5yPJtn4jL2_4BcbaN7thQn6EMsJN1czfHvtKrjS9c5KNNQtncYJZTBkzomXRoOxM6FQsGSbDoT7AZ-9w2E8Hg29ID0d0V7SGxxv030SO5Vup7_ncNTHleIUzVhYIGXUTcuw6yhvTe4sDb4M5l4R2idvBO33fzPyNph4DQbWerprrtC-OealqiHzy3BqxlWwdh0l-27u4Bb60WVQYLdMe81C98z3P7Qj_28O3kY3W9SM94Kb30EbtrqLfvoDl2yBK2um2BML_CYNDDgcd9wG_DXIaWDodAqsqjb0Fxh-fHZaI5fYU-0hoJuRxv6QK-zIwd1kNQ471C77eBjWsnDL7veR1Q00tVBZ8axZQPJtfQ-dHYxOB-O4PWQiNoAk01hRrmGMZZmilOfCqDI3jBcFIC1AM0xoUu6mRhPFobtPrWaGE5HzhCrw_RK-76PNalbZhwgTaNDKtCggiGElIVqLMmNGqMQKLnQSocPOIWSbeBlUo0lLBICykKEkJKGSSEGlhPyXbf5LKhM5OIYbWYReeI9aRqTmU8fRE1yeT97J_ZNPkw8nPJGnEdpac7nlAzmkg7AIPes8UELD4laLVGVnTS2FcNJAIo3Qg-CYq3f2uIfCOxx59_r7xFydlu6vR_84vsfoRmAMOvLRFtpczBv7BCDkQj_1lf4XBmtQsw |
link.rule.ids | 310,311,315,786,790,795,796,1382,23958,23959,25170,27957,27958,46329,46753 |
linkProvider | Wiley-Blackwell |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwvV1bb9MwFLbGJsFeuIjLAoP5gSF4SJf4EmcFIW1tR8vWbkKdmHix7MThoSJFSysxfsd-MMd20lK0Bx4QUpVWjeMT28fHn48_HyP0kvBCc-uoihPOQ1bs6zA1KVwA2gPaALVJ7Qbn4Sjpn7OPF_xiDVXNXhgfH2LhcLM9w9lr28GtQ3pvGTXUrp2GEWUwZ06Ji40Gk2dCoWXJLu0I-wM-B4Nu2O91XUR62qOtqNU53aWHJExuoQ2wEtzNwz4tY07RhPklUkatY4bdRmktc28h8bWX94bQNnknaLv9m5T3XsZbkLAy1m3YZvthuZeqguov_LkZNwHbVZzsBrqje-i6qSLPb5m05jPdyn7-ET3yP9fhfXS3Bs74wGv6A7Rmyofo2p25ZHJcmmyCHbfA7dPAAMVxQ2_A331EDQzjTo5VWaf-BjOQrzbcyBV2bHtIaJ3S2J1zhS0_uPFXY79J7aqNu345C9cEf5dZNQdrC_0VT-czKL-pHqHzo9640w_rcybCDMBkHCrKNUyzDFOU8lRkqkgzxvMcwBYAGiY0KfbjTBPFYcSPjWYZJyLlEVWg_gV8P0br5bQ0WwgTsGlFnOeQJGMFIVqLImGZUJERXOgoQINGI2RdeOkDR5OaCwBtIX1LSEIlkYJKCfUv6_qXVEaycwo3kgC9ciq1yEhdTixNT3D5efRBHp59GR2f8UiOA7S9onOLB1IoB2EB2mlUUIJtsQtGqjTTeSWFsNGBRBygJ14zl-_soA-Fdxg6_fr7wtxcluavp_84vx10pz8ensiTwej4Gdr0BELLRdpG67PLuXkOiHKmXzgL8AtCDVTV |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwvV1bb9MwFLbGJk28cBG3wGB-YAge0iW-xFlBSFvT0jLWVWgTEy-WnTg8VKRTLxLjb8AP5thOWor2wANCqtKqcXxy7HPsz_bnY4SeE15qbieq4oTzkJUHOkxNCheA9oA2wGxSu8H5ZJj0z9n7C36xgabNXhgfH2I54WY9w7XX1sEvi3J_FTTULp2GEWUwZE6JC40GY2dCoWLJHu0I-wM-h4Ms7HczF5CedmkranVO9-gRCZMbaIsllFhPyD6uQk7RhPkVUkbtvAzbRmktc38p8aWX94rQNnkjaLv9m5S3XsZrkLDW1W3ZWvtmqZdqBqVf-mMzrsO16zDZ9XO92-hHU0Ke3jJuLea6lX__I3jk_y3CO-hWDZvxobfzu2jDVPfQT3fikilwZfIxdswCt0sDAxDHDbkBX_p4Ghh6nQKrqk79FcYfX2ywkSvsuPaQ0E5JY3fKFbbs4Ga2GvstaldtnPnFLFzT-11mswW0teCteLKYg_pmdh-d97pnnX5YnzIR5gAl41BRrmGQZZiilKciV2WaM14UALUAzjChSXkQ55ooDv19bDTLOREpj6gC4y_h-wHarCaVeYQwgRatjIsCkuSsJERrUSYsFyoyggsdBWjQGISslZc-bDSpmQBQF9LXhCRUEimolFD-si5_SWUkO6dwIwnQC2dRy4zUdGxJeoLLT8N38mj0eXg84pE8C9DOmsktH0hBD8ICtNtYoISWxS4XqcpMFjMphI0NJOIAPfSGuXpnB3wovMOJM6-_V-Z6XZq_Hv_j_HbR9ijryQ-D4fETdNOzBy0RaQdtzqcL8xTg5Fw_c_7_C87MU4Q |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=proceeding&rft.title=Head+%26+neck&rft.atitle=Planned+neck+dissection+for+advanced+primary+head+and+neck+malignancy+treated+with+organ+preservation+therapy+%3A+Disease+control+and+survival+outcomes&rft.au=NEWKIRK%2C+Kenneth+A&rft.au=CULLEN%2C+Kevin+J&rft.au=HARTER%2C+K.+William&rft.au=PICKEN%2C+Catherine+A&rft.date=2001-02-01&rft.pub=John+Wiley+%26+Sons&rft.issn=1043-3074&rft.eissn=1097-0347&rft.volume=23&rft.issue=2&rft.spage=73&rft.epage=79&rft_id=info:doi/10.1002%2F1097-0347%28200102%2923%3A2%3C73%3A%3AAID-HED1001%3E3.0.CO%3B2-6&rft.externalDBID=n%2Fa&rft.externalDocID=852724 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1043-3074&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1043-3074&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1043-3074&client=summon |