Pigment epithelium proliferation in retinal detachment (massive periretinal proliferation)

Cell proliferation and membrane formation found in the posterior parts of the eye after production of retinal detachment in owl monkey eyes had either the characteristics of macrophages or of membrane-forming epithelial cells. The proliferating cells originated from pigment epithelium. These membran...

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Bibliographic Details
Published inAmerican journal of ophthalmology Vol. 80; no. 1; p. 1
Main Authors Machemer, R, Laqua, H
Format Journal Article
LanguageEnglish
Published United States 01.07.1975
Subjects
Animals
Autoradiography
Cell Division
Disease Models, Animal
DNA - biosynthesis
Epithelial Cells
Epithelium - pathology
Epithelium - ultrastructure
Fibroblasts - pathology
Fibroblasts - ultrastructure
Haplorhini
Macrophages - pathology
Macrophages - ultrastructure
Membranes
Microscopy, Electron
Retina - pathology
Retinal Detachment - pathology
Thymidine - metabolism
Vitreous Body - pathology
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Summary:Cell proliferation and membrane formation found in the posterior parts of the eye after production of retinal detachment in owl monkey eyes had either the characteristics of macrophages or of membrane-forming epithelial cells. The proliferating cells originated from pigment epithelium. These membranes caused folding of the retina and strand formation in the vitreous cavity. Since cell proliferation was present on all available surfaces, such as the upper and under surface of the retina, and along vitreous surfaces, we propose to call this entity "massive periretinal proliferation" (MPP).
ISSN:0002-9394
DOI:10.1016/0002-9394(75)90862-4