Distribution and susceptibility of bacterial urinary tract infections in Dakar, Senegal

• Published in: International journal of antimicrobial agents Vol. 20; no. 5; pp. 339 - 347
• Main Authors: Dromigny, J.A., Nabeth, P., Perrier Gros Claude, J.D.
• Format: Journal Article
• Language: English
• Published: London Elsevier B.V 01.11.2002; Amsterdam Elsevier; New York, NY
• Subjects: Adolescent; Adult; Anti-Bacterial Agents - pharmacology; Antibacterial agents; Antibiotic resistance; Antibiotics. Antiinfectious agents. Antiparasitic agents; Bacterial Infections - epidemiology; Bacterial Infections - microbiology; Biological and medical sciences; Child; Child, Preschool; Drug Resistance, Multiple, Bacterial; Female; Gram-Negative Bacteria - drug effects; Gram-Positive Bacteria - drug effects; Humans; Infant; Male; Medical sciences; Microbial Sensitivity Tests; Middle Aged; Pharmacology. Drug treatments; Retrospective Studies; Senegal; Senegal - epidemiology; Urinary Tract - microbiology; Urinary tract infection; Urinary Tract Infections - epidemiology; Urinary Tract Infections - microbiology; Senegal; Africa; Senegal; Urinary tract infection; Antibiotic resistance; Infection; Human; Resistance; Sensitivity resistance; Bacteriosis; Urinary tract disease; Urinary tract; Epidemiology; In vitro; Clinical isolate; Biological activity
• ISSN: 0924-8579; 1872-7913
• DOI: 10.1016/S0924-8579(02)00196-6

To assess the current distribution and antibiotic susceptibility patterns of uropathogens isolated from community-acquired urinary tract infections (UTIs) in Dakar, a retrospective study was carried out at the biomedical laboratory of Institut Pasteur de Dakar between January 1999 and December 2000. The most important finding, among Enterobacteriaceae, was the emergence of multidrug resistant strains (extended-spectrum β-lactamase and both chromosomally derepressed and plasmid mediated cephalosporinase producing strains) affecting 2.9% of all Enterobacteriaceae. Of Gram-positive cocci, 15% of Staphylococcus aureus were methicillin-resistant. Our data show the original distribution of uropathogens from UTIs in ambulant patients and the emergence of multidrug resistant strains in Dakar.