Exploration of the risk factor for infarction after revascularization in moyamoya disease

• Published in: Annals of medicine (Helsinki) Vol. 56; no. 1; p. 2362872
• Main Authors: Sun, Tao, Zeng, Qiuhua, Huang, Lixin, Sun, Jun, Wu, Zhimin, Zhang, Baoyu, Ling, Cong, Chen, Chuan, Wang, Hui
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis Group 01.12.2024
• Subjects: Adolescent; Adult; Cerebral Infarction - epidemiology; Cerebral Infarction - etiology; Cerebral Revascularization - adverse effects; Cerebral Revascularization - methods; Child; Female; Humans; Hypotension - epidemiology; Hypotension - etiology; Male; Middle Aged; Moyamoya disease; Moyamoya Disease - complications; Moyamoya Disease - surgery; new or expanded infarction; Posterior Cerebral Artery - surgery; Postoperative Complications - epidemiology; Postoperative Complications - etiology; Retrospective Studies; revascularization; risk factor; Risk Factors; Young Adult; revascularization; new or expanded infarction; Moyamoya disease; risk factor
• ISSN: 0785-3890; 1365-2060; 1365-2060
• DOI: 10.1080/07853890.2024.2362872

Eventually, 108 consecutive patients received 174 surgeries were enrolled, experienced new or expanded infarction occured in 13 (7.47%) surgeries, which showed higher Suzuki stage on the non-operative side, more posterior cerebral artery (PCA) involvement, and more intraoperative hypotension compared to those without infarction(  < .05). The Suzuki stage on the non-operative side had the highest area under the curve (AUC) of 0.737, with a sensitivity of 0.692 and specificity of 0.783. Combination of the three factors showed better efficiency, with an AUC of 0.762, a sensitivity of 0.692, and a specificity of 0.907. Revascularization was a safe option for patients with MMD, higher Suzuki stage on the non-operative side, PCA involvement, and intraoperative hypotension might be the risk factors for new or expanded infarction after revascularization in patients with MMD.