Primary extramedullary plasmacytoma of the eyelid conjunctiva – A case report and review of the literature
Extramedullary plasmacytomas (EMPs) are uncommon plasma cell tumors that develop in soft tissue as isolated tumors without osseous involvement while secondary lesions are associated with systemic multiple myeloma (MM). Primary extramedullary lesions are most commonly found in upper respiratory tract...
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Published in | Annals of medicine and surgery Vol. 55; pp. 1 - 4 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
England
Elsevier Ltd
01.07.2020
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | Extramedullary plasmacytomas (EMPs) are uncommon plasma cell tumors that develop in soft tissue as isolated tumors without osseous involvement while secondary lesions are associated with systemic multiple myeloma (MM). Primary extramedullary lesions are most commonly found in upper respiratory tract, gastrointestinal tract and lymph nodes. They can be found either in patients with history of MM or preceding the manifestation of a systemic disease. Orbital manifestation of the lesion is rare but conjunctival involvement is very unusual. The reported cases in the English-written literature are only five cases. Herein, we report the sixth case of primary EMP in a middle-aged adult who presented with a lesion confined to the conjunctiva, unremarkable present and past medical history, and confirmed tissue diagnosis. In addition, a review and summary of the previously reported cases in the literature is presented. We aim to attract the attention of ophthalmic surgeons to consider plasmacytoma within the differential diagnosis of a conjunctival lesion.
•Extramedullary plasmacytomas (EMP) are isolated primary soft tissue plasma cell tumors without osseous involvement.•Secondary lesions are associated with systemic multiple myeloma.•The conjunctiva is a very unusual location for primary lesions.•We are reporting the sixth case of conjunctival primary EMP.•All cases including ours are summarized. |
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ISSN: | 2049-0801 2049-0801 |
DOI: | 10.1016/j.amsu.2020.04.028 |