Spontaneous regression of angiolymphoid hyperplasia with eosinophilia (AHLE): A case report

• Published in: Annals of medicine and surgery Vol. 66; p. 102376
• Main Authors: Slimani, Yasmine, Hali, Fouzia, Sid'Ahmed Tolba, Cheikh, Marnissi, Farida, Chiheb, Soumiya
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.2021; Elsevier
• Subjects: ALHE; Angiolymphoid hyperplasia with eosinophilia; Case Report; Vascular tumor; Vascular tumor; Angiolymphoid hyperplasia with eosinophilia; ALHE
• ISSN: 2049-0801; 2049-0801
• DOI: 10.1016/j.amsu.2021.102376

and importance - Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare benign microvascular proliferation. It is clinically characterized by intradermal or subcutaneous papules and/or nodules. Treatment consists mainly of surgery or laser therapy, with a high recurrence rate. Spontaneous regression is rare but possible. A 72-year-old man presented for an erythematous plaque on his scalp. Physical examination demonstrated a large angiomatous indurated subcutaneous plaque. The lesion was not pulsatile. The doppler ultrasound revealed no underlying vascular malformation. The biopsy revealed an ALHE. No further treatment was carried out. During the follow-up, the lesion gradually subsided. After one-year follow-up, the lesion had regressed with no sign of recurrence. There are different treatment modalities for AHLE management, including surgical excision, cryotherapy and lasers. However, none of these modalities has provided consistent results and recurrence after treatment is common.). Rare instances of spontaneous regression have been reported. Given the rarity of cases of spontaneous resolution, ALHE may be considered as a chronic condition, especially since recurrences are frequent. A “wait and see” approach can be proposed in some specific situations. •AHLE is a rare benign microvascular proliferation.•Treatment consists of surgery or laser therapy, with a hight recurrence rate.•Spontaneous regression is rare but possible.•We report a case and review the literature of spontaneously regressive ALHE cases.