No detection of CD4-independent human immunodeficiency virus 1 envelope glycoproteins in brain tissue of patients with or without neurological complications

Macrophage (mac)-tropic human immnunodeficiency virus type 1 (HIV-1) and simian immnunodeficiency virus (SIV) in brain are associated with neurological disease. Mac-tropic HIV-1 evolves enhanced CD4 interactions that enable macrophage infection via CD4, which is in low abundance. In contrast, mac-tr...

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Published inArchives of virology Vol. 164; no. 2; pp. 473 - 482
Main Authors Quitadamo, Briana, Peters, Paul J., Koch, Matthew, Luzuriaga, Katherine, Cheng-Mayer, Cecilia, Clapham, Paul R., Gonzalez-Perez, Maria Paz
Format Journal Article
LanguageEnglish
Published Vienna Springer Vienna 01.02.2019
Springer Nature B.V
Subjects
Biomedical and Life Sciences
Biomedicine
Brain - metabolism
Brain - virology
CCR5 protein
CD4 antigen
CD4 Antigens - genetics
CD4 Antigens - metabolism
Glycoproteins
HIV
HIV Envelope Protein gp120 - genetics
HIV Envelope Protein gp120 - metabolism
HIV Infections - complications
HIV Infections - virology
HIV-1 - classification
HIV-1 - genetics
HIV-1 - isolation & purification
HIV-1 - metabolism
Human immunodeficiency virus
Humans
Infections
Infectious Diseases
Macrophages
Macrophages - metabolism
Macrophages - virology
Medical Microbiology
Nervous System Diseases - diagnosis
Nervous System Diseases - etiology
Nervous System Diseases - virology
Neurological complications
Original
Original Article
Phylogeny
Receptors, CCR5 - genetics
Receptors, CCR5 - metabolism
Receptors, Virus - genetics
Receptors, Virus - metabolism
Tropism
Virology
Online AccessGet full text

Cover

Abstract Macrophage (mac)-tropic human immnunodeficiency virus type 1 (HIV-1) and simian immnunodeficiency virus (SIV) in brain are associated with neurological disease. Mac-tropic HIV-1 evolves enhanced CD4 interactions that enable macrophage infection via CD4, which is in low abundance. In contrast, mac-tropic SIV is associated with CD4-independent infection via direct CCR5 binding. Recently, mac-tropic simian-human immunodeficiency virus (SHIV) from macaque brain was also reported to infect cells via CCR5 without CD4. Since SHIV envelope proteins (Envs) are derived from HIV-1, we tested more than 100 HIV-1 clade B Envs for infection of CD4-negative, CCR5 + Cf2Th/CCR5 cells. However, no infection was detected. Our data suggest that there are differences in the evolution of mac-tropism in SIV and SHIV compared to HIV-1 clade B due to enhanced interactions with CCR5 and CD4, respectively.
AbstractList Macrophage (mac)-tropic human immnunodeficiency virus type 1 (HIV-1) and simian immnunodeficiency virus (SIV) in brain are associated with neurological disease. Mac-tropic HIV-1 evolves enhanced CD4 interactions that enable macrophage infection via CD4, which is in low abundance. In contrast, mac-tropic SIV is associated with CD4-independent infection via direct CCR5 binding. Recently, mac-tropic simian-human immunodeficiency virus (SHIV) from macaque brain was also reported to infect cells via CCR5 without CD4. Since SHIV envelope proteins (Envs) are derived from HIV-1, we tested more than 100 HIV-1 clade B Envs for infection of CD4-negative, CCR5 + Cf2Th/CCR5 cells. However, no infection was detected. Our data suggest that there are differences in the evolution of mac-tropism in SIV and SHIV compared to HIV-1 clade B due to enhanced interactions with CCR5 and CD4, respectively.
Macrophage (mac)-tropic human immnunodeficiency virus type 1 (HIV-1) and simian immnunodeficiency virus (SIV) in brain are associated with neurological disease. Mac-tropic HIV-1 evolves enhanced CD4 interactions that enable macrophage infection via CD4, which is in low abundance. In contrast, mac-tropic SIV is associated with CD4-independent infection via direct CCR5 binding. Recently, mac-tropic simian-human immunodeficiency virus (SHIV) from macaque brain was also reported to infect cells via CCR5 without CD4. Since SHIV envelope proteins (Envs) are derived from HIV-1, we tested more than 100 HIV-1 clade B Envs for infection of CD4-negative, CCR5+ Cf2Th/CCR5 cells. However, no infection was detected. Our data suggest that there are differences in the evolution of mac-tropism in SIV and SHIV compared to HIV-1 clade B due to enhanced interactions with CCR5 and CD4, respectively.
Macrophage (mac)-tropic human immnunodeficiency virus type 1 (HIV-1) and simian immnunodeficiency virus (SIV) in brain are associated with neurological disease. Mac-tropic HIV-1 evolves enhanced CD4 interactions that enable macrophage infection via CD4, which is in low abundance. In contrast, mac-tropic SIV is associated with CD4-independent infection via direct CCR5 binding. Recently, mac-tropic simian-human immunodeficiency virus (SHIV) from macaque brain was also reported to infect cells via CCR5 without CD4. Since SHIV envelope proteins (Envs) are derived from HIV-1, we tested more than 100 HIV-1 clade B Envs for infection of CD4-negative, CCR5 Cf2Th/CCR5 cells. However, no infection was detected. Our data suggest that there are differences in the evolution of mac-tropism in SIV and SHIV compared to HIV-1 clade B due to enhanced interactions with CCR5 and CD4, respectively.
Author Koch, Matthew
Clapham, Paul R.
Cheng-Mayer, Cecilia
Luzuriaga, Katherine
Gonzalez-Perez, Maria Paz
Quitadamo, Briana
Peters, Paul J.
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Cites_doi 10.1186/1742-4690-9-20
10.1111/j.1750-3639.2002.tb00461.x
10.1128/JVI.00755-17
10.1128/JVI.02133-08
10.1016/j.virol.2010.05.006
10.1038/nri1527
10.1186/1742-4690-5-5
10.1084/jem.193.8.905
10.1128/JVI.01237-14
10.1128/JVI.76.6.2595-2605.2002
10.1097/00002030-199509000-00004
10.1007/978-1-4614-0980-9_10
10.1128/JVI.76.12.6277-6292.2002
10.1016/S0002-9440(10)63767-4
10.1128/JVI.02477-13
10.1128/JVI.75.21.10073-10089.2001
10.1128/JVI.02680-14
10.1128/JVI.74.22.10852-10859.2000
10.1016/j.jviromet.2015.02.017
10.1128/JVI.02328-05
10.1007/s004010051113
10.1128/JVI.05170-11
10.1097/00002030-200302140-00002
10.1016/S0960-5428(06)80268-8
10.1016/S0140-6736(94)91222-X
10.1128/JVI.00185-10
10.1128/JVI.00106-11
10.1073/pnas.0605513103
10.1097/COH.0000000000000361
10.1002/ana.410390606
10.1212/WNL.42.9.1736
10.1128/JVI.74.21.10074-10080.2000
10.1093/brain/awh695
10.1371/journal.ppat.1002286
10.3109/13550289609146909
10.1189/jlb.0612308
10.1080/135502801753248114
10.1189/jlb.0306148
10.1128/JVI.78.13.6915-6926.2004
10.1097/00002030-200307040-00005
10.1016/j.coviro.2016.07.012
10.1212/WNL.44.3_Part_1.481
10.1128/JVI.74.23.10984-10993.2000
10.1093/infdis/168.4.818
10.1111/imr.12484
10.1093/molbev/msw054
10.1073/pnas.96.9.5215
10.1002/ana.410380510
10.1126/science.1241475
10.1128/JVI.01834-12
10.2353/ajpath.2006.050240
10.1002/ana.21697
10.1016/j.virol.2014.03.024
10.1212/WNL.44.3_Part_1.474
10.1128/JVI.00841-17
10.1128/AAC.46.6.1896-1905.2002
10.1128/JVI.71.8.5790-5798.1997
10.12688/f1000research.10651.1
10.1128/JVI.66.6.3531-3537.1992
10.1128/JVI.73.9.7795-7804.1999
10.1128/JVI.73.10.8120-8126.1999
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References Tornatore, Chandra, Berger, Major (CR56) 1994; 44
Peters, Sullivan, Duenas-Decamp, Bhattacharya, Ankghuambom, Brown, Luzuriaga, Bell, Simmonds, Ball, Clapham (CR40) 2006; 80
Salimi, Roche, Webb, Gray, Chikere, Sterjovski, Ellett, Wesselingh, Ramsland, Lee, Churchill, Gorry (CR48) 2013; 93
Quitadamo, Peters, Repik, O’Connell, Mou, Koch, Somasundaran, Brody, Luzuriaga, Wallace, Wang, Lu, McCauley, Luban, Duenas-Decamp, Gonzalez-Perez, Clapham (CR43) 2018; 92
Glass, Fedor, Wesselingh, McArthur (CR19) 1995; 38
Duenas-Decamp, Peters, Burton, Clapham (CR13) 2009; 83
Duenas-Decamp, Clapham (CR14) 2010; 84
O’Doherty, Swiggard, Malim (CR38) 2000; 74
Roche, Jakobsen, Sterjovski, Ellett, Posta, Lee, Jubb, Westby, Lewin, Ramsland, Churchill, Gorry (CR46) 2011; 85
Yen, Mefford, Hoxie, Williams, Desrosiers, Gabuzda (CR61) 2014; 458–459
Wei, Decker, Liu, Zhang, Arani, Kilby, Saag, Wu, Shaw, Kappes (CR57) 2002; 46
Flaherty, Hauer, Mankowski, Zink, Clements (CR18) 1997; 71
Kolchinsky, Mirzabekov, Farzan, Kiprilov, Cayabyab, Mooney, Choe, Sodroski (CR28) 1999; 73
An, Groves, Giometto, Beckett, Scaravilli (CR1) 1999; 98
McCoy, Burton (CR32) 2017; 275
Ranki, Nyberg, Ovod, Haltia, Elovaara, Raininko, Haapasalo, Krohn (CR44) 1995; 9
Reeves, Hibbitts, Simmons, McKnight, Azevedo-Pereira, Moniz-Pereira, Clapham (CR45) 1999; 73
Gorry, Taylor, Holm, Mehle, Morgan, Cayabyab, Farzan, Wang, Bell, Kunstman, Moore, Wolinsky, Gabuzda (CR25) 2002; 76
Joseph, Arrildt, Swanstrom, Schnell, Lee, Hoxie, Swanstrom (CR27) 2014; 88
CR6
Lu, Manning, Arthos (CR31) 1999; 29
Sterjovski, Roche, Churchill, Ellett, Farrugia, Gray, Cowley, Poumbourios, Lee, Wesselingh, Cunningham, Ramsland, Gorry (CR51) 2010; 404
Gonzalez-Perez, Peters, O’Connell, Silva, Harbison, Cummings Macri, Kaliyaperumal, Luzuriaga, Clapham (CR21) 2017; 91
Williams, Lackner, Mallard (CR59) 2016; 19
Takahashi, Wesselingh, Griffin, McArthur, Johnson, Glass (CR52) 1996; 39
Schnell, Joseph, Spudich, Price, Swanstrom (CR49) 2011; 7
Churchill, Wesselingh, Cowley, Pardo, McArthur, Brew, Gorry (CR7) 2009; 66
Clapham, McKnight, Weiss (CR8) 1992; 66
Mori, Rosenzweig, Desrosiers (CR35) 2000; 74
Thomas, Shotton, Weiss, Clapham, McKnight (CR55) 2003; 17
Coutu, Finzi (CR10) 2015; 215–216
Davis, Hjelle, Miller, Palmer, Llewellyn, Merlin, Young, Mills, Wachsman, Wiley (CR11) 1992; 42
Gonzalez-Scarano, Martin-Garcia (CR22) 2005; 5
McCrossan, Marsden, Carnie, Minnis, Hansoti, Anthony, Brettle, Bell, Simmonds (CR34) 2006; 129
Bell, Busuttil, Ironside, Rebus, Donaldson, Simmonds, Peutherer (CR3) 1993; 168
Bissel, Wang, Trichel, Murphey-Corb, Wiley (CR4) 2006; 168
Cosenza, Zhao, Si, Lee (CR9) 2002; 12
Puffer, Pohlmann, Edinger, Carlin, Sanchez, Reitter, Watry, Fox, Desrosiers, Doms (CR42) 2002; 76
Williams, Corey, Westmoreland, Pauley, Knight, deBakker, Alvarez, Lackner (CR60) 2001; 193
Boyd, Peterson, Haggarty, Jordan, Hogan, Goo, Hoxie, Overbaugh (CR5) 2015; 89
Wilen, Tilton, Doms (CR58) 2012; 726
Goodenow, Collman (CR23) 2006; 80
Zhuang, Leda, Tsai, Knight, Harbison, Gettie, Blanchard, Westmoreland, Cheng-Mayer (CR62) 2014; 88
Donaldson, Bell, Ironside, Brettle, Robertson, Busuttil, Simmonds (CR12) 1994; 343
Tan, Zhu, Li, Chen, Han, Kufareva, Li, Ma, Fenalti, Li, Zhang, Xie, Yang, Jiang, Cherezov, Liu, Stevens, Zhao, Wu (CR54) 2013; 341
Guo, Wang, Yu, Wu (CR26) 2011; 85
Lee, Sharron, Montaner, Weissman, Doms (CR30) 1999; 96
Lane, Sasseville, Smith, Vogel, Pauley, Heyes, Lackner (CR29) 1996; 2
O’Connell, Repik, Reeves, Gonzalez-Perez, Quitadamo, Anton, Duenas-Decamp, Peters, Lin, Zolla-Pazner, Corti, Wallace, Wang, Kong, Lu, Clapham (CR37) 2013; 87
Saito, Sharer, Epstein, Michaels, Mintz, Louder, Golding, Cvetkovich, Blumberg (CR47) 1994; 44
Morner, Thomas, Bjorling, Munson, Lucas, McKnight (CR36) 2003; 17
Peters, Bhattacharya, Hibbitts, Dittmar, Simmons, Bell, Simmonds, Clapham (CR39) 2004; 78
Peters, Duenas-Decamp, Sullivan, Brown, Ankghuambom, Luzuriaga, Robinson, Burton, Bell, Simmonds, Ball, Clapham (CR41) 2008; 5
Gorry, Bristol, Zack, Ritola, Swanstrom, Birch, Bell, Bannert, Crawford, Wang, Schols, De Clercq, Kunstman, Wolinsky, Gabuzda (CR24) 2001; 75
McCoy, McKnight (CR33) 2017; 12
Sharer, Saito, Epstein, Blumberg (CR50) 1994; 4
Gonzalez-Perez, O’Connell, Lin, Sullivan, Bell, Simmonds, Clapham (CR20) 2012; 9
Fischer-Smith, Croul, Adeniyi, Rybicka, Morgello, Khalili, Rappaport (CR17) 2004; 164
Fischer-Smith, Croul, Sverstiuk, Capini, L’Heureux, Regulier, Richardson, Amini, Morgello, Khalili, Rappaport (CR16) 2001; 7
Bannert, Schenten, Craig, Sodroski (CR2) 2000; 74
Dunfee, Thomas, Gorry, Wang, Taylor, Kunstman, Wolinsky, Gabuzda (CR15) 2006; 103
Kumar, Stecher, Tamura (CR53) 2016; 33
M Coutu (4094_CR10) 2015; 215–216
MT Flaherty (4094_CR18) 1997; 71
JE Bell (4094_CR3) 1993; 168
A Morner (4094_CR36) 2003; 17
O O’Connell (4094_CR37) 2013; 87
S Kumar (4094_CR53) 2016; 33
S Lu (4094_CR31) 1999; 29
PJ Peters (4094_CR40) 2006; 80
PR Gorry (4094_CR24) 2001; 75
PJ Peters (4094_CR41) 2008; 5
K Takahashi (4094_CR52) 1996; 39
MJ Duenas-Decamp (4094_CR13) 2009; 83
K Mori (4094_CR35) 2000; 74
M McCrossan (4094_CR34) 2006; 129
PJ Yen (4094_CR61) 2014; 458–459
LR Sharer (4094_CR50) 1994; 4
RL Dunfee (4094_CR15) 2006; 103
SB Joseph (4094_CR27) 2014; 88
DF Boyd (4094_CR5) 2015; 89
Y Saito (4094_CR47) 1994; 44
MJ Churchill (4094_CR7) 2009; 66
PJ Peters (4094_CR39) 2004; 78
MP Gonzalez-Perez (4094_CR20) 2012; 9
MM Goodenow (4094_CR23) 2006; 80
JH Lane (4094_CR29) 1996; 2
JD Glass (4094_CR19) 1995; 38
JD Reeves (4094_CR45) 1999; 73
LE McCoy (4094_CR32) 2017; 275
LE Davis (4094_CR11) 1992; 42
BA Puffer (4094_CR42) 2002; 76
P Kolchinsky (4094_CR28) 1999; 73
A Ranki (4094_CR44) 1995; 9
KC Williams (4094_CR60) 2001; 193
LE McCoy (4094_CR33) 2017; 12
4094_CR6
SJ Bissel (4094_CR4) 2006; 168
B Lee (4094_CR30) 1999; 96
K Zhuang (4094_CR62) 2014; 88
B Quitadamo (4094_CR43) 2018; 92
CB Wilen (4094_CR58) 2012; 726
MJ Duenas-Decamp (4094_CR14) 2010; 84
PR Gorry (4094_CR25) 2002; 76
ER Thomas (4094_CR55) 2003; 17
F Gonzalez-Scarano (4094_CR22) 2005; 5
MA Cosenza (4094_CR9) 2002; 12
C Tornatore (4094_CR56) 1994; 44
K Williams (4094_CR59) 2016; 19
J Guo (4094_CR26) 2011; 85
PR Clapham (4094_CR8) 1992; 66
YK Donaldson (4094_CR12) 1994; 343
G Schnell (4094_CR49) 2011; 7
T Fischer-Smith (4094_CR16) 2001; 7
U O’Doherty (4094_CR38) 2000; 74
X Wei (4094_CR57) 2002; 46
J Sterjovski (4094_CR51) 2010; 404
N Bannert (4094_CR2) 2000; 74
MP Gonzalez-Perez (4094_CR21) 2017; 91
Q Tan (4094_CR54) 2013; 341
SF An (4094_CR1) 1999; 98
M Roche (4094_CR46) 2011; 85
H Salimi (4094_CR48) 2013; 93
T Fischer-Smith (4094_CR17) 2004; 164
References_xml – volume: 71
  start-page: 5790
  year: 1997
  end-page: 5798
  ident: CR18
  article-title: Molecular and biological characterization of a neurovirulent molecular clone of simian immunodeficiency virus
  publication-title: J Virol
  contributor:
    fullname: Clements
– volume: 9
  start-page: 20
  year: 2012
  ident: CR20
  article-title: Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue
  publication-title: Retrovirology
  doi: 10.1186/1742-4690-9-20
  contributor:
    fullname: Clapham
– volume: 12
  start-page: 442
  year: 2002
  end-page: 455
  ident: CR9
  article-title: Human brain parenchymal microglia express CD14 and CD45 and are productively infected by HIV-1 in HIV-1 encephalitis
  publication-title: Brain Pathol
  doi: 10.1111/j.1750-3639.2002.tb00461.x
  contributor:
    fullname: Lee
– volume: 66
  start-page: 3531
  year: 1992
  end-page: 3537
  ident: CR8
  article-title: Human immunodeficiency virus type 2 infection and fusion of CD4-negative human cell lines: induction and enhancement by soluble CD4
  publication-title: J Virol
  contributor:
    fullname: Weiss
– volume: 91
  start-page: e00755-00717
  year: 2017
  ident: CR21
  article-title: Identification of emerging macrophage-tropic HIV-1 R5 variants in brain tissue of AIDS patients without severe neurological complications
  publication-title: J Virol
  doi: 10.1128/JVI.00755-17
  contributor:
    fullname: Clapham
– volume: 83
  start-page: 2575
  year: 2009
  end-page: 2583
  ident: CR13
  article-title: Determinants flanking the CD4 binding loop modulate macrophage tropism of human immunodeficiency virus type 1 R5 envelopes
  publication-title: J Virol
  doi: 10.1128/JVI.02133-08
  contributor:
    fullname: Clapham
– volume: 404
  start-page: 269
  year: 2010
  end-page: 278
  ident: CR51
  article-title: An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 envelopes
  publication-title: Virology
  doi: 10.1016/j.virol.2010.05.006
  contributor:
    fullname: Gorry
– volume: 5
  start-page: 69
  year: 2005
  end-page: 81
  ident: CR22
  article-title: The neuropathogenesis of AIDS
  publication-title: Nat Rev Immunol
  doi: 10.1038/nri1527
  contributor:
    fullname: Martin-Garcia
– volume: 5
  start-page: 5
  year: 2008
  ident: CR41
  article-title: Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors
  publication-title: Retrovirology
  doi: 10.1186/1742-4690-5-5
  contributor:
    fullname: Clapham
– volume: 193
  start-page: 905
  year: 2001
  end-page: 915
  ident: CR60
  article-title: Perivascular macrophages are the primary cell type productively infected by simian immunodeficiency virus in the brains of macaques: implications for the neuropathogenesis of AIDS
  publication-title: J Exp Med
  doi: 10.1084/jem.193.8.905
  contributor:
    fullname: Lackner
– volume: 88
  start-page: 8407
  year: 2014
  end-page: 8420
  ident: CR62
  article-title: Emergence of CD4 independence envelopes and astrocyte infection in R5 simian-human immunodeficiency virus model of encephalitis
  publication-title: J Virol
  doi: 10.1128/JVI.01237-14
  contributor:
    fullname: Cheng-Mayer
– volume: 76
  start-page: 2595
  year: 2002
  end-page: 2605
  ident: CR42
  article-title: CD4 independence of simian immunodeficiency virus Envs is associated with macrophage tropism, neutralization sensitivity, and attenuated pathogenicity
  publication-title: J Virol
  doi: 10.1128/JVI.76.6.2595-2605.2002
  contributor:
    fullname: Doms
– volume: 9
  start-page: 1001
  year: 1995
  end-page: 1008
  ident: CR44
  article-title: Abundant expression of HIV Nef and Rev proteins in brain astrocytes in vivo is associated with dementia
  publication-title: AIDS
  doi: 10.1097/00002030-199509000-00004
  contributor:
    fullname: Krohn
– volume: 726
  start-page: 223
  year: 2012
  end-page: 242
  ident: CR58
  article-title: Molecular mechanisms of HIV entry
  publication-title: Adv Exp Med Biol
  doi: 10.1007/978-1-4614-0980-9_10
  contributor:
    fullname: Doms
– volume: 76
  start-page: 6277
  year: 2002
  end-page: 6292
  ident: CR25
  article-title: Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate
  publication-title: J Virol
  doi: 10.1128/JVI.76.12.6277-6292.2002
  contributor:
    fullname: Gabuzda
– volume: 164
  start-page: 2089
  year: 2004
  end-page: 2099
  ident: CR17
  article-title: Macrophage/microglial accumulation and proliferating cell nuclear antigen expression in the central nervous system in human immunodeficiency virus encephalopathy
  publication-title: Am J Pathol
  doi: 10.1016/S0002-9440(10)63767-4
  contributor:
    fullname: Rappaport
– volume: 88
  start-page: 1858
  year: 2014
  end-page: 1869
  ident: CR27
  article-title: Quantification of entry phenotypes of macrophage-tropic HIV-1 across a wide range of CD4 densities
  publication-title: J Virol
  doi: 10.1128/JVI.02477-13
  contributor:
    fullname: Swanstrom
– volume: 75
  start-page: 10073
  year: 2001
  end-page: 10089
  ident: CR24
  article-title: Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity
  publication-title: J Virol
  doi: 10.1128/JVI.75.21.10073-10089.2001
  contributor:
    fullname: Gabuzda
– volume: 89
  start-page: 894
  year: 2015
  end-page: 907
  ident: CR5
  article-title: Mutations in HIV-1 envelope that enhance entry with the macaque CD4 receptor alter antibody recognition by disrupting quaternary interactions within the trimer
  publication-title: J Virol
  doi: 10.1128/JVI.02680-14
  contributor:
    fullname: Overbaugh
– volume: 74
  start-page: 10852
  year: 2000
  end-page: 10859
  ident: CR35
  article-title: Mechanisms for adaptation of simian immunodeficiency virus to replication in alveolar macrophages
  publication-title: J Virol
  doi: 10.1128/JVI.74.22.10852-10859.2000
  contributor:
    fullname: Desrosiers
– volume: 215–216
  start-page: 37
  year: 2015
  end-page: 44
  ident: CR10
  article-title: HIV-1 gp120 dimers decrease the overall affinity of gp120 preparations for CD4-induced ligands
  publication-title: J Virol Methods
  doi: 10.1016/j.jviromet.2015.02.017
  contributor:
    fullname: Finzi
– volume: 80
  start-page: 6324
  year: 2006
  end-page: 6332
  ident: CR40
  article-title: Non-macrophage-tropic human immunodeficiency virus type 1 R5 envelopes predominate in blood, lymph nodes, and semen: implications for transmission and pathogenesis
  publication-title: J Virol
  doi: 10.1128/JVI.02328-05
  contributor:
    fullname: Clapham
– volume: 98
  start-page: 481
  year: 1999
  end-page: 487
  ident: CR1
  article-title: Detection and localisation of HIV-1 DNA and RNA in fixed adult AIDS brain by polymerase chain reaction/in situ hybridisation technique
  publication-title: Acta Neuropathol (Berl)
  doi: 10.1007/s004010051113
  contributor:
    fullname: Scaravilli
– volume: 85
  start-page: 9824
  year: 2011
  end-page: 9833
  ident: CR26
  article-title: Spinoculation triggers dynamic actin and cofilin activity that facilitates HIV-1 infection of transformed and resting CD4 T cells
  publication-title: J Virol
  doi: 10.1128/JVI.05170-11
  contributor:
    fullname: Wu
– volume: 17
  start-page: 291
  year: 2003
  end-page: 300
  ident: CR55
  article-title: CD4-dependent and CD4-independent HIV-2: consequences for neutralization
  publication-title: AIDS
  doi: 10.1097/00002030-200302140-00002
  contributor:
    fullname: McKnight
– volume: 4
  start-page: 283
  year: 1994
  end-page: 285
  ident: CR50
  article-title: Detection of HIV-1 DNA in pediatric AIDS brain tissue by two-step ISPCR
  publication-title: Adv Neuroimmunol
  doi: 10.1016/S0960-5428(06)80268-8
  contributor:
    fullname: Blumberg
– volume: 343
  start-page: 383
  year: 1994
  end-page: 385
  ident: CR12
  article-title: Redistribution of HIV outside the lymphoid system with onset of AIDS
  publication-title: Lancet
  doi: 10.1016/S0140-6736(94)91222-X
  contributor:
    fullname: Simmonds
– volume: 84
  start-page: 9608
  year: 2010
  end-page: 9612
  ident: CR14
  article-title: HIV-1 gp120 determinants proximal to the CD4 binding site shift protective glycans that are targeted by monoclonal antibody, 2G12
  publication-title: J Virol
  doi: 10.1128/JVI.00185-10
  contributor:
    fullname: Clapham
– volume: 85
  start-page: 4330
  year: 2011
  end-page: 4342
  ident: CR46
  article-title: HIV-1 escape from the CCR5 antagonist maraviroc associated with an altered and less-efficient mechanism of gp120-CCR5 engagement that attenuates macrophage tropism
  publication-title: J Virol
  doi: 10.1128/JVI.00106-11
  contributor:
    fullname: Gorry
– volume: 103
  start-page: 15160
  year: 2006
  end-page: 15165
  ident: CR15
  article-title: The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.0605513103
  contributor:
    fullname: Gabuzda
– volume: 12
  start-page: 195
  year: 2017
  end-page: 202
  ident: CR33
  article-title: Lessons learned from humoral responses of HIV patients
  publication-title: Curr Opin HIV AIDS
  doi: 10.1097/COH.0000000000000361
  contributor:
    fullname: McKnight
– volume: 39
  start-page: 705
  year: 1996
  end-page: 711
  ident: CR52
  article-title: Localization of HIV-1 in human brain using polymerase chain reaction/in situ hybridization and immunocytochemistry
  publication-title: Ann Neurol
  doi: 10.1002/ana.410390606
  contributor:
    fullname: Glass
– volume: 42
  start-page: 1736
  year: 1992
  end-page: 1739
  ident: CR11
  article-title: Early viral brain invasion in iatrogenic human immunodeficiency virus infection
  publication-title: Neurology
  doi: 10.1212/WNL.42.9.1736
  contributor:
    fullname: Wiley
– volume: 74
  start-page: 10074
  year: 2000
  end-page: 10080
  ident: CR38
  article-title: Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding
  publication-title: J Virol
  doi: 10.1128/JVI.74.21.10074-10080.2000
  contributor:
    fullname: Malim
– volume: 29
  start-page: 355
  year: 1999
  end-page: 374
  ident: CR31
  article-title: Antigen engineering in DNA immunization
  publication-title: Methods Mol Med (Humana Press Inc, Totowa, NJ)
  contributor:
    fullname: Arthos
– volume: 129
  start-page: 503
  year: 2006
  end-page: 516
  ident: CR34
  article-title: An immune control model for viral replication in the CNS during presymptomatic HIV infection
  publication-title: Brain J Neurol
  doi: 10.1093/brain/awh695
  contributor:
    fullname: Simmonds
– volume: 7
  start-page: e1002286
  year: 2011
  ident: CR49
  article-title: HIV-1 replication in the central nervous system occurs in two distinct cell types
  publication-title: PLoS Pathog
  doi: 10.1371/journal.ppat.1002286
  contributor:
    fullname: Swanstrom
– volume: 2
  start-page: 423
  year: 1996
  end-page: 432
  ident: CR29
  article-title: Neuroinvasion by simian immunodeficiency virus coincides with increased numbers of perivascular macrophages/microglia and intrathecal immune activation
  publication-title: J Neurovirol
  doi: 10.3109/13550289609146909
  contributor:
    fullname: Lackner
– volume: 93
  start-page: 113
  year: 2013
  end-page: 126
  ident: CR48
  article-title: Macrophage-tropic HIV-1 variants from brain demonstrate alterations in the way gp120 engages both CD4 and CCR5
  publication-title: J Leukoc Biol
  doi: 10.1189/jlb.0612308
  contributor:
    fullname: Gorry
– volume: 7
  start-page: 528
  year: 2001
  end-page: 541
  ident: CR16
  article-title: CNS invasion by CD14+/CD16+ peripheral blood-derived monocytes in HIV dementia: perivascular accumulation and reservoir of HIV infection
  publication-title: J Neurovirol
  doi: 10.1080/135502801753248114
  contributor:
    fullname: Rappaport
– volume: 80
  start-page: 965
  year: 2006
  end-page: 972
  ident: CR23
  article-title: HIV-1 coreceptor preference is distinct from target cell tropism: a dual-parameter nomenclature to define viral phenotypes
  publication-title: J Leukoc Biol
  doi: 10.1189/jlb.0306148
  contributor:
    fullname: Collman
– ident: CR6
– volume: 78
  start-page: 6915
  year: 2004
  end-page: 6926
  ident: CR39
  article-title: Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enhanced tropism and fusigenicity for macrophages
  publication-title: J Virol
  doi: 10.1128/JVI.78.13.6915-6926.2004
  contributor:
    fullname: Clapham
– volume: 17
  start-page: 1451
  year: 2003
  end-page: 1455
  ident: CR36
  article-title: Productive HIV-2 infection in the brain is restricted to macrophages/microglia
  publication-title: AIDS
  doi: 10.1097/00002030-200307040-00005
  contributor:
    fullname: McKnight
– volume: 73
  start-page: 7795
  year: 1999
  end-page: 7804
  ident: CR45
  article-title: Primary human immunodeficiency virus type 2 (HIV-2) isolates infect CD4- negative cells via CCR5 and CXCR4: comparison with HIV-1 and simian immunodeficiency virus and relevance to cell tropism In vivo
  publication-title: J Virol
  contributor:
    fullname: Clapham
– volume: 19
  start-page: 92
  year: 2016
  end-page: 98
  ident: CR59
  article-title: Non-human primate models of SIV infection and CNS neuropathology
  publication-title: Curr Opin Virol
  doi: 10.1016/j.coviro.2016.07.012
  contributor:
    fullname: Mallard
– volume: 44
  start-page: 481
  year: 1994
  end-page: 487
  ident: CR56
  article-title: HIV-1 infection of subcortical astrocytes in the pediatric central nervous system
  publication-title: Neurology
  doi: 10.1212/WNL.44.3_Part_1.481
  contributor:
    fullname: Major
– volume: 74
  start-page: 10984
  year: 2000
  end-page: 10993
  ident: CR2
  article-title: The level of CD4 expression limits infection of primary rhesus monkey macrophages by a T-tropic simian immunodeficiency virus and macrophagetropic human immunodeficiency viruses
  publication-title: J Virol
  doi: 10.1128/JVI.74.23.10984-10993.2000
  contributor:
    fullname: Sodroski
– volume: 168
  start-page: 818
  year: 1993
  end-page: 824
  ident: CR3
  article-title: Human immunodeficiency virus and the brain: investigation of virus load and neuropathologic changes in pre-AIDS subjects
  publication-title: J Infect Dis
  doi: 10.1093/infdis/168.4.818
  contributor:
    fullname: Peutherer
– volume: 275
  start-page: 11
  year: 2017
  end-page: 20
  ident: CR32
  article-title: Identification and specificity of broadly neutralizing antibodies against HIV
  publication-title: Immunol Rev
  doi: 10.1111/imr.12484
  contributor:
    fullname: Burton
– volume: 33
  start-page: 1870
  year: 2016
  end-page: 1874
  ident: CR53
  article-title: MEGA7: molecular evolutionary genetics analysis version 7.0 for bigger datasets
  publication-title: Mol Biol Evol
  doi: 10.1093/molbev/msw054
  contributor:
    fullname: Tamura
– volume: 96
  start-page: 5215
  year: 1999
  end-page: 5220
  ident: CR30
  article-title: Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.96.9.5215
  contributor:
    fullname: Doms
– volume: 38
  start-page: 755
  year: 1995
  end-page: 762
  ident: CR19
  article-title: Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia
  publication-title: Ann Neurol
  doi: 10.1002/ana.410380510
  contributor:
    fullname: McArthur
– volume: 73
  start-page: 8120
  year: 1999
  end-page: 8126
  ident: CR28
  article-title: Adaptation of a CCR5-using, primary human immunodeficiency virus type 1 isolate for CD4-independent replication
  publication-title: J Virol
  contributor:
    fullname: Sodroski
– volume: 341
  start-page: 1387
  year: 2013
  end-page: 1390
  ident: CR54
  article-title: Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex
  publication-title: Science
  doi: 10.1126/science.1241475
  contributor:
    fullname: Wu
– volume: 87
  start-page: 187
  year: 2013
  end-page: 198
  ident: CR37
  article-title: Efficiency of bridging-sheet recruitment explains HIV-1 R5 envelope glycoprotein sensitivity to soluble CD4 and macrophage tropism
  publication-title: J Virol
  doi: 10.1128/JVI.01834-12
  contributor:
    fullname: Clapham
– volume: 168
  start-page: 1553
  year: 2006
  end-page: 1569
  ident: CR4
  article-title: Longitudinal analysis of monocyte/macrophage infection in simian immunodeficiency virus-infected, CD8+ T-cell-depleted macaques that develop lentiviral encephalitis
  publication-title: Am J Pathol
  doi: 10.2353/ajpath.2006.050240
  contributor:
    fullname: Wiley
– volume: 66
  start-page: 253
  year: 2009
  end-page: 258
  ident: CR7
  article-title: Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia
  publication-title: Ann Neurol
  doi: 10.1002/ana.21697
  contributor:
    fullname: Gorry
– volume: 458–459
  start-page: 53
  year: 2014
  end-page: 68
  ident: CR61
  article-title: Identification and characterization of a macrophage-tropic SIV envelope glycoprotein variant in blood from early infection in SIVmac251-infected macaques
  publication-title: Virology
  doi: 10.1016/j.virol.2014.03.024
  contributor:
    fullname: Gabuzda
– volume: 44
  start-page: 474
  year: 1994
  end-page: 481
  ident: CR47
  article-title: Overexpression of nef as a marker for restricted HIV-1 infection of astrocytes in postmortem pediatric central nervous tissues
  publication-title: Neurology
  doi: 10.1212/WNL.44.3_Part_1.474
  contributor:
    fullname: Blumberg
– volume: 92
  start-page: e00841-17
  year: 2018
  ident: CR43
  article-title: HIV-1 R5 macrophage-tropic envelope glycoprotein trimers bind CD4 with high affinity, while the CD4 binding site on non-macrophage-tropic, T- tropic R5 envelopes is occluded
  publication-title: J Virol
  doi: 10.1128/JVI.00841-17
  contributor:
    fullname: Clapham
– volume: 46
  start-page: 1896
  year: 2002
  end-page: 1905
  ident: CR57
  article-title: Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy
  publication-title: Antimicrob Agents Chemother
  doi: 10.1128/AAC.46.6.1896-1905.2002
  contributor:
    fullname: Kappes
– volume: 42
  start-page: 1736
  year: 1992
  ident: 4094_CR11
  publication-title: Neurology
  doi: 10.1212/WNL.42.9.1736
  contributor:
    fullname: LE Davis
– volume: 2
  start-page: 423
  year: 1996
  ident: 4094_CR29
  publication-title: J Neurovirol
  doi: 10.3109/13550289609146909
  contributor:
    fullname: JH Lane
– volume: 9
  start-page: 1001
  year: 1995
  ident: 4094_CR44
  publication-title: AIDS
  doi: 10.1097/00002030-199509000-00004
  contributor:
    fullname: A Ranki
– volume: 103
  start-page: 15160
  year: 2006
  ident: 4094_CR15
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.0605513103
  contributor:
    fullname: RL Dunfee
– volume: 726
  start-page: 223
  year: 2012
  ident: 4094_CR58
  publication-title: Adv Exp Med Biol
  doi: 10.1007/978-1-4614-0980-9_10
  contributor:
    fullname: CB Wilen
– volume: 98
  start-page: 481
  year: 1999
  ident: 4094_CR1
  publication-title: Acta Neuropathol (Berl)
  doi: 10.1007/s004010051113
  contributor:
    fullname: SF An
– volume: 83
  start-page: 2575
  year: 2009
  ident: 4094_CR13
  publication-title: J Virol
  doi: 10.1128/JVI.02133-08
  contributor:
    fullname: MJ Duenas-Decamp
– volume: 88
  start-page: 1858
  year: 2014
  ident: 4094_CR27
  publication-title: J Virol
  doi: 10.1128/JVI.02477-13
  contributor:
    fullname: SB Joseph
– volume: 5
  start-page: 5
  year: 2008
  ident: 4094_CR41
  publication-title: Retrovirology
  doi: 10.1186/1742-4690-5-5
  contributor:
    fullname: PJ Peters
– volume: 38
  start-page: 755
  year: 1995
  ident: 4094_CR19
  publication-title: Ann Neurol
  doi: 10.1002/ana.410380510
  contributor:
    fullname: JD Glass
– volume: 215–216
  start-page: 37
  year: 2015
  ident: 4094_CR10
  publication-title: J Virol Methods
  doi: 10.1016/j.jviromet.2015.02.017
  contributor:
    fullname: M Coutu
– volume: 164
  start-page: 2089
  year: 2004
  ident: 4094_CR17
  publication-title: Am J Pathol
  doi: 10.1016/S0002-9440(10)63767-4
  contributor:
    fullname: T Fischer-Smith
– volume: 92
  start-page: e00841-17
  year: 2018
  ident: 4094_CR43
  publication-title: J Virol
  doi: 10.1128/JVI.00841-17
  contributor:
    fullname: B Quitadamo
– volume: 343
  start-page: 383
  year: 1994
  ident: 4094_CR12
  publication-title: Lancet
  doi: 10.1016/S0140-6736(94)91222-X
  contributor:
    fullname: YK Donaldson
– volume: 168
  start-page: 818
  year: 1993
  ident: 4094_CR3
  publication-title: J Infect Dis
  doi: 10.1093/infdis/168.4.818
  contributor:
    fullname: JE Bell
– volume: 88
  start-page: 8407
  year: 2014
  ident: 4094_CR62
  publication-title: J Virol
  doi: 10.1128/JVI.01237-14
  contributor:
    fullname: K Zhuang
– volume: 17
  start-page: 1451
  year: 2003
  ident: 4094_CR36
  publication-title: AIDS
  doi: 10.1097/00002030-200307040-00005
  contributor:
    fullname: A Morner
– volume: 71
  start-page: 5790
  year: 1997
  ident: 4094_CR18
  publication-title: J Virol
  doi: 10.1128/JVI.71.8.5790-5798.1997
  contributor:
    fullname: MT Flaherty
– volume: 33
  start-page: 1870
  year: 2016
  ident: 4094_CR53
  publication-title: Mol Biol Evol
  doi: 10.1093/molbev/msw054
  contributor:
    fullname: S Kumar
– volume: 87
  start-page: 187
  year: 2013
  ident: 4094_CR37
  publication-title: J Virol
  doi: 10.1128/JVI.01834-12
  contributor:
    fullname: O O’Connell
– volume: 275
  start-page: 11
  year: 2017
  ident: 4094_CR32
  publication-title: Immunol Rev
  doi: 10.1111/imr.12484
  contributor:
    fullname: LE McCoy
– volume: 46
  start-page: 1896
  year: 2002
  ident: 4094_CR57
  publication-title: Antimicrob Agents Chemother
  doi: 10.1128/AAC.46.6.1896-1905.2002
  contributor:
    fullname: X Wei
– ident: 4094_CR6
  doi: 10.12688/f1000research.10651.1
– volume: 66
  start-page: 253
  year: 2009
  ident: 4094_CR7
  publication-title: Ann Neurol
  doi: 10.1002/ana.21697
  contributor:
    fullname: MJ Churchill
– volume: 85
  start-page: 4330
  year: 2011
  ident: 4094_CR46
  publication-title: J Virol
  doi: 10.1128/JVI.00106-11
  contributor:
    fullname: M Roche
– volume: 129
  start-page: 503
  year: 2006
  ident: 4094_CR34
  publication-title: Brain J Neurol
  doi: 10.1093/brain/awh695
  contributor:
    fullname: M McCrossan
– volume: 76
  start-page: 6277
  year: 2002
  ident: 4094_CR25
  publication-title: J Virol
  doi: 10.1128/JVI.76.12.6277-6292.2002
  contributor:
    fullname: PR Gorry
– volume: 78
  start-page: 6915
  year: 2004
  ident: 4094_CR39
  publication-title: J Virol
  doi: 10.1128/JVI.78.13.6915-6926.2004
  contributor:
    fullname: PJ Peters
– volume: 5
  start-page: 69
  year: 2005
  ident: 4094_CR22
  publication-title: Nat Rev Immunol
  doi: 10.1038/nri1527
  contributor:
    fullname: F Gonzalez-Scarano
– volume: 44
  start-page: 474
  year: 1994
  ident: 4094_CR47
  publication-title: Neurology
  doi: 10.1212/WNL.44.3_Part_1.474
  contributor:
    fullname: Y Saito
– volume: 89
  start-page: 894
  year: 2015
  ident: 4094_CR5
  publication-title: J Virol
  doi: 10.1128/JVI.02680-14
  contributor:
    fullname: DF Boyd
– volume: 91
  start-page: e00755-00717
  year: 2017
  ident: 4094_CR21
  publication-title: J Virol
  doi: 10.1128/JVI.00755-17
  contributor:
    fullname: MP Gonzalez-Perez
– volume: 12
  start-page: 442
  year: 2002
  ident: 4094_CR9
  publication-title: Brain Pathol
  doi: 10.1111/j.1750-3639.2002.tb00461.x
  contributor:
    fullname: MA Cosenza
– volume: 80
  start-page: 965
  year: 2006
  ident: 4094_CR23
  publication-title: J Leukoc Biol
  doi: 10.1189/jlb.0306148
  contributor:
    fullname: MM Goodenow
– volume: 44
  start-page: 481
  year: 1994
  ident: 4094_CR56
  publication-title: Neurology
  doi: 10.1212/WNL.44.3_Part_1.481
  contributor:
    fullname: C Tornatore
– volume: 80
  start-page: 6324
  year: 2006
  ident: 4094_CR40
  publication-title: J Virol
  doi: 10.1128/JVI.02328-05
  contributor:
    fullname: PJ Peters
– volume: 17
  start-page: 291
  year: 2003
  ident: 4094_CR55
  publication-title: AIDS
  doi: 10.1097/00002030-200302140-00002
  contributor:
    fullname: ER Thomas
– volume: 66
  start-page: 3531
  year: 1992
  ident: 4094_CR8
  publication-title: J Virol
  doi: 10.1128/JVI.66.6.3531-3537.1992
  contributor:
    fullname: PR Clapham
– volume: 19
  start-page: 92
  year: 2016
  ident: 4094_CR59
  publication-title: Curr Opin Virol
  doi: 10.1016/j.coviro.2016.07.012
  contributor:
    fullname: K Williams
– volume: 12
  start-page: 195
  year: 2017
  ident: 4094_CR33
  publication-title: Curr Opin HIV AIDS
  doi: 10.1097/COH.0000000000000361
  contributor:
    fullname: LE McCoy
– volume: 75
  start-page: 10073
  year: 2001
  ident: 4094_CR24
  publication-title: J Virol
  doi: 10.1128/JVI.75.21.10073-10089.2001
  contributor:
    fullname: PR Gorry
– volume: 93
  start-page: 113
  year: 2013
  ident: 4094_CR48
  publication-title: J Leukoc Biol
  doi: 10.1189/jlb.0612308
  contributor:
    fullname: H Salimi
– volume: 74
  start-page: 10074
  year: 2000
  ident: 4094_CR38
  publication-title: J Virol
  doi: 10.1128/JVI.74.21.10074-10080.2000
  contributor:
    fullname: U O’Doherty
– volume: 9
  start-page: 20
  year: 2012
  ident: 4094_CR20
  publication-title: Retrovirology
  doi: 10.1186/1742-4690-9-20
  contributor:
    fullname: MP Gonzalez-Perez
– volume: 73
  start-page: 7795
  year: 1999
  ident: 4094_CR45
  publication-title: J Virol
  doi: 10.1128/JVI.73.9.7795-7804.1999
  contributor:
    fullname: JD Reeves
– volume: 168
  start-page: 1553
  year: 2006
  ident: 4094_CR4
  publication-title: Am J Pathol
  doi: 10.2353/ajpath.2006.050240
  contributor:
    fullname: SJ Bissel
– volume: 7
  start-page: 528
  year: 2001
  ident: 4094_CR16
  publication-title: J Neurovirol
  doi: 10.1080/135502801753248114
  contributor:
    fullname: T Fischer-Smith
– volume: 73
  start-page: 8120
  year: 1999
  ident: 4094_CR28
  publication-title: J Virol
  doi: 10.1128/JVI.73.10.8120-8126.1999
  contributor:
    fullname: P Kolchinsky
– volume: 96
  start-page: 5215
  year: 1999
  ident: 4094_CR30
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.96.9.5215
  contributor:
    fullname: B Lee
– volume: 4
  start-page: 283
  year: 1994
  ident: 4094_CR50
  publication-title: Adv Neuroimmunol
  doi: 10.1016/S0960-5428(06)80268-8
  contributor:
    fullname: LR Sharer
– volume: 39
  start-page: 705
  year: 1996
  ident: 4094_CR52
  publication-title: Ann Neurol
  doi: 10.1002/ana.410390606
  contributor:
    fullname: K Takahashi
– volume: 458–459
  start-page: 53
  year: 2014
  ident: 4094_CR61
  publication-title: Virology
  doi: 10.1016/j.virol.2014.03.024
  contributor:
    fullname: PJ Yen
– volume: 84
  start-page: 9608
  year: 2010
  ident: 4094_CR14
  publication-title: J Virol
  doi: 10.1128/JVI.00185-10
  contributor:
    fullname: MJ Duenas-Decamp
– volume: 74
  start-page: 10984
  year: 2000
  ident: 4094_CR2
  publication-title: J Virol
  doi: 10.1128/JVI.74.23.10984-10993.2000
  contributor:
    fullname: N Bannert
– volume: 193
  start-page: 905
  year: 2001
  ident: 4094_CR60
  publication-title: J Exp Med
  doi: 10.1084/jem.193.8.905
  contributor:
    fullname: KC Williams
– volume: 29
  start-page: 355
  year: 1999
  ident: 4094_CR31
  publication-title: Methods Mol Med (Humana Press Inc, Totowa, NJ)
  contributor:
    fullname: S Lu
– volume: 74
  start-page: 10852
  year: 2000
  ident: 4094_CR35
  publication-title: J Virol
  doi: 10.1128/JVI.74.22.10852-10859.2000
  contributor:
    fullname: K Mori
– volume: 404
  start-page: 269
  year: 2010
  ident: 4094_CR51
  publication-title: Virology
  doi: 10.1016/j.virol.2010.05.006
  contributor:
    fullname: J Sterjovski
– volume: 341
  start-page: 1387
  year: 2013
  ident: 4094_CR54
  publication-title: Science
  doi: 10.1126/science.1241475
  contributor:
    fullname: Q Tan
– volume: 7
  start-page: e1002286
  year: 2011
  ident: 4094_CR49
  publication-title: PLoS Pathog
  doi: 10.1371/journal.ppat.1002286
  contributor:
    fullname: G Schnell
– volume: 85
  start-page: 9824
  year: 2011
  ident: 4094_CR26
  publication-title: J Virol
  doi: 10.1128/JVI.05170-11
  contributor:
    fullname: J Guo
– volume: 76
  start-page: 2595
  year: 2002
  ident: 4094_CR42
  publication-title: J Virol
  doi: 10.1128/JVI.76.6.2595-2605.2002
  contributor:
    fullname: BA Puffer
SSID ssj0003035
Score 2.2891223
Snippet Macrophage (mac)-tropic human immnunodeficiency virus type 1 (HIV-1) and simian immnunodeficiency virus (SIV) in brain are associated with neurological...
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proquest
crossref
pubmed
springer
SourceType Open Access Repository
Aggregation Database
Index Database
Publisher
StartPage 473
SubjectTerms Biomedical and Life Sciences
Biomedicine
Brain - metabolism
Brain - virology
CCR5 protein
CD4 antigen
CD4 Antigens - genetics
CD4 Antigens - metabolism
Glycoproteins
HIV
HIV Envelope Protein gp120 - genetics
HIV Envelope Protein gp120 - metabolism
HIV Infections - complications
HIV Infections - virology
HIV-1 - classification
HIV-1 - genetics
HIV-1 - isolation & purification
HIV-1 - metabolism
Human immunodeficiency virus
Humans
Infections
Infectious Diseases
Macrophages
Macrophages - metabolism
Macrophages - virology
Medical Microbiology
Nervous System Diseases - diagnosis
Nervous System Diseases - etiology
Nervous System Diseases - virology
Neurological complications
Original
Original Article
Phylogeny
Receptors, CCR5 - genetics
Receptors, CCR5 - metabolism
Receptors, Virus - genetics
Receptors, Virus - metabolism
Tropism
Virology
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Title No detection of CD4-independent human immunodeficiency virus 1 envelope glycoproteins in brain tissue of patients with or without neurological complications
URI https://link.springer.com/article/10.1007/s00705-018-4094-1
https://www.ncbi.nlm.nih.gov/pubmed/30415390
https://www.proquest.com/docview/2131636924
https://search.proquest.com/docview/2132256275
https://pubmed.ncbi.nlm.nih.gov/PMC6369005
Volume 164
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