Association between sensory nerve action potential and lumbar dorsal root ganglion area

• Published in: Journal of clinical neuroscience Vol. 59; pp. 37 - 40
• Main Authors: Beom, Jaewon, Kim, Sujin, Suh, Hoon Chang, Kim, Don-Kyu, Kang, Si Hyun, Lee, Shi-Uk, Lee, Sang Yoon
• Format: Journal Article
• Language: English
• Published: Scotland Elsevier Ltd 01.01.2019
• Subjects: Action potential; Action Potentials; Adult; Electrodiagnosis; Ganglia; Ganglia, Spinal - diagnostic imaging; Ganglia, Spinal - physiology; Humans; Lumbosacral Region - diagnostic imaging; Lumbosacral Region - physiology; Male; Middle Aged; Sensory receptor cells; Sensory Receptor Cells - physiology; Spinal nerve roots; Electrodiagnosis; Action potential; Spinal nerve roots; Sensory receptor cells; Ganglia
• ISSN: 0967-5868; 1532-2653
• DOI: 10.1016/j.jocn.2018.11.019

•No studies have investigated the relationship between DRG and SNAP amplitude.•The area of L5 and S1-DRGs may be positively correlated with SNAP amplitude.•It can be applied to establishing the values of SNAP amplitude according to DRGs. To quantify the cross-sectional area (CSA) of lumbar dorsal root ganglion (DRG) by magnetic resonance imaging (MRI) and investigate the relationship between the cross-sectional area (CSA) of DRGs and sensory nerve action potentials (SNAP) amplitude in the lower extremities. Thirty-eight DRGs (20 L5 roots and 18 S1 roots) in 10 adult subjects were reviewed retrospectively. The CSA of the DRG was calculated from MR images of the coronal plane. SNAP amplitudes of the superficial peroneal nerve and sural nerve were corresponded to L5 and S1-DRGs. The mean CSA of DRGs was 66.6 ± 13.7 mm2 in L5-DRG and 79.5 ± 14.3 mm2 in S1-DRG. The means of SNAP amplitudes were 19.6 ± 6.2 μV in superficial peroneal nerves and 24.6 ± 9.0 μV in sural nerves. In multivariate regression analysis, the CSA of DRGs had a significant correlation with SNAP amplitude. The area of L5 and S1-DRGs may be positively correlated with SNAP amplitude.