mCPP-induced hypophagia in rats is unaffected by the profile of dietary unsaturated fatty acids

• Published in: Pharmacology, biochemistry and behavior Vol. 73; no. 3; pp. 545 - 550
• Main Authors: Rice, H.B, Corwin, R.L
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.10.2002; Elsevier Science
• Subjects: 5-HT 2C; Agonist; Animals; Biological and medical sciences; Body Weight - drug effects; Diet; Dietary Fats - pharmacology; Dose-Response Relationship, Drug; Energy Intake - drug effects; Essential fatty acid; Fat; Fatty Acids, Omega-3 - pharmacology; Fatty Acids, Unsaturated - pharmacology; Feeding Behavior - drug effects; Flaxseed; Food intake; General and cellular metabolism. Vitamins; Ingestive behavior; Linoleic acid; Linolenic acid; Male; Medical sciences; Neuropharmacology; Neurotransmitters. Neurotransmission. Receptors; Pharmacology. Drug treatments; Piperazines - pharmacology; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin - drug effects; Safflower; Serotonin; Serotonin Receptor Agonists - pharmacology; Serotoninergic system; Safflower; Agonist; Linolenic acid; Flaxseed; Serotonin; Food intake; Fat; Ingestive behavior; Essential fatty acid; 5-HT 2C; Linoleic acid; Intraperitoneal administration; Feeding behavior; Rat; Body weight; Rodentia; Biological activity; Vertebrata; Mammalia; Animal; 5-HT1B serotonin receptor; Unsaturated fatty acid; Anorectic; Piperazine derivatives; 5-HT2C serotonin receptor

The n-3 and n-6 polyunsaturated fatty acids (PUFAs) have been shown to modify central serotonergic parameters relevant to ingestive behavior. Evidence suggests an association between the 5-HT 2C receptor and fat intake. The present research sought to examine the role of the 5-HT 2C receptor subtype...