Total Synthesis of Brevetoxin A: Part 1: First Generation Strategy and Construction of BCD Ring System
Dissection of brevetoxin A at the nine‐membered ring site (ring E) formed the basis of the first generation strategy for the total synthesis of this molecule. Unfortuately the planned hydroxy dithioketal cyclization to form the crucial nonacene did not proceed as anticipated and this approach was di...
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Published in | Chemistry : a European journal Vol. 5; no. 2; pp. 599 - 617 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Weinheim
WILEY-VCH Verlag
01.02.1999
WILEY‐VCH Verlag Wiley |
Subjects | |
Online Access | Get full text |
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Summary: | Dissection of brevetoxin A at the nine‐membered ring site (ring E) formed the basis of the first generation strategy for the total synthesis of this molecule. Unfortuately the planned hydroxy dithioketal cyclization to form the crucial nonacene did not proceed as anticipated and this approach was discontinued. |
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Bibliography: | istex:91114298672018C2EE8148F35F16F3E606A81311 ark:/67375/WNG-TZ4VNLLF-K ArticleID:CHEM599 |
ISSN: | 0947-6539 1521-3765 |
DOI: | 10.1002/(SICI)1521-3765(19990201)5:2<599::AID-CHEM599>3.0.CO;2-N |