The role of estrogen in migraine: a review and hypothesis

The epidemiological, clinical and basic science evidence for a role of estrogen in migraine is reviewed. The hypothesis is put forward that estrogen exerts its influence by modulating sympathetic control of the cerebral vasculature.

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Bibliographic Details
Published inCephalalgia Vol. 4; no. 4; p. 227
Main Authors Welch, K M, Darnley, D, Simkins, R T
Format Journal Article
LanguageEnglish
Published England 01.12.1984
Subjects
Cerebrovascular Circulation
Estrogens - physiology
Female
Humans
Menarche
Menstrual Cycle
Migraine Disorders - physiopathology
Progesterone - physiology
Receptors, Adrenergic - physiology
Sympathetic Nervous System - physiopathology
Vasoconstriction
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Summary:The epidemiological, clinical and basic science evidence for a role of estrogen in migraine is reviewed. The hypothesis is put forward that estrogen exerts its influence by modulating sympathetic control of the cerebral vasculature.
ISSN:0333-1024
DOI:10.1046/j.1468-2982.1984.0404227.x