Location of collateral sprouting of donor nerve following end-to-side neurorrhaphy
Various studies have demonstrated collateral regeneration of the donor nerve following end‐to‐side neurorrhaphy, but the location of collateral sprouting remains controversial. In a rat end‐to‐side neurorrhaphy model we isolated nerve fibers from the donor nerve at the neurorrhaphy site utilizing a...
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Published in | Muscle & nerve Vol. 38; no. 5; pp. 1506 - 1509 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Hoboken
Wiley Subscription Services, Inc., A Wiley Company
01.11.2008
Wiley |
Subjects | |
Online Access | Get full text |
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Summary: | Various studies have demonstrated collateral regeneration of the donor nerve following end‐to‐side neurorrhaphy, but the location of collateral sprouting remains controversial. In a rat end‐to‐side neurorrhaphy model we isolated nerve fibers from the donor nerve at the neurorrhaphy site utilizing a micro‐tease technique. We found that axons sprouted collaterally from a myelinated nerve fiber at the node of Ranvier. Based on this preliminary result we conclude that myelinated nerve fibers could sprout collateral branches at the node of Ranvier at an end‐to‐side neurorrhaphy site. These findings show that end‐to‐side neurorrhaphy may be an alternative for peripheral nerve repair. Muscle Nerve, 2008. |
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Bibliography: | ark:/67375/WNG-PKD2QS98-6 ArticleID:MUS21116 istex:D8756530BC48600709AB1FB831A74E2CE62BDAE4 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0148-639X 1097-4598 |
DOI: | 10.1002/mus.21116 |