Periampullary Adenocarcinoid: Diagnostic Dilemma

ABSTRACT The growth in periampullary region needs proper evaluation as they can arise from duodenum, pancreas and extra hepatic biliary tree. We have reported a case of adenocarcinoid of duodenum presenting as periampullary growth with obstructive jaundice. Histologically, tumor displayed biphasic p...

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Published inJournal of laboratory physicians Vol. 5; no. 2; pp. 139 - 141
Main Authors Krishnappa, Rashmi, Metikurke, Sudha Horakerappa, Honnappa, Sridhar, Hosakote, Rudresh, Chandrashekar, Nagesh Kumar Talkad
Format Journal Article
LanguageEnglish
Published A-12, Second Floor, Sector -2, NOIDA -201301, India Thieme Medical and Scientific Publishers Private Ltd 01.07.2013
Medknow Publications
Medknow Publications and Media Pvt. Ltd
Thieme Medical Publishers Inc
Medknow Publications & Media Pvt Ltd
Thieme Medical and Scientific Publishers Pvt. Ltd
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Summary:ABSTRACT The growth in periampullary region needs proper evaluation as they can arise from duodenum, pancreas and extra hepatic biliary tree. We have reported a case of adenocarcinoid of duodenum presenting as periampullary growth with obstructive jaundice. Histologically, tumor displayed biphasic pattern, i.e. tubuloglandular architecture with admixed sheets of neuroendocrine cells without pancreas and extra hepatic biliary tree involvement. The adenocarcinoids are of great diagnostic challenges for the pathologist interpreting endoscopic biopsy for the frequent misinterpretation as negative due to their submucosal location or as adenocarcinomas due to tubulo-glandular architecture.
ISSN:0974-2727
0974-7826
DOI:10.4103/0974-2727.119875