A comprehensive protein expression profile of extracellular matrix biomaterial derived from porcine urinary bladder

• Published in: Regenerative medicine Vol. 7; no. 2; pp. 159 - 166
• Main Authors: Marçal, Helder, Ahmed, Tania, Badylak, Stephen F, Tottey, Stephen, Foster, L John R
• Format: Journal Article
• Language: English
• Published: England Future Medicine Ltd 01.03.2012
• Subjects: Animals; Biocompatible Materials - metabolism; biomaterial; Biomedical materials; Bladder; ECM; Extracellular matrix; Extracellular Matrix - metabolism; Extracellular Matrix Proteins - classification; Extracellular Matrix Proteins - metabolism; Health aspects; Male; Physiological aspects; Protein Transport; proteomics; Proteomics - methods; scaffold; Subcellular Fractions - metabolism; Sus scrofa - metabolism; tissue engineering; tissue regeneration; UBM; Urinary Bladder - metabolism; urinary bladder matrix; Australia; United States

To generate a comprehensive profile of the protein composition of xenogeneic biomaterial, derived from porcine urinary bladder matrix (UBM). Tunica layers and muscularis mucosa were removed from bladders using mechanical delamination. UBM was prepared using a solution of peracetic acid in ethanol, l...