An efficient green synthesis of novel 1H-imidazo[1,2-a]imidazole-3-amine and imidazo[2,1-c][1,2,4]triazole-5-amine derivatives via Strecker reaction under controlled microwave heating
A highly efficient multi-component one-pot synthesis of novel 1 -imidazo[1,2- ]imidazole-3-amine and imidazo[2,1- ][1,2,4]triazole-5-amine derivatives has been developed through the reaction of easily available aromatic aldehydes, benzoyl cyanide and either 2-aminoimidazole-4,5-dicarbonitrile or 3-a...
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Published in | Green processing and synthesis Vol. 8; no. 1; pp. 297 - 301 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Berlin
De Gruyter
28.01.2019
Walter de Gruyter GmbH |
Subjects | |
Online Access | Get full text |
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Summary: | A highly efficient multi-component one-pot synthesis of novel 1
-imidazo[1,2-
]imidazole-3-amine and imidazo[2,1-
][1,2,4]triazole-5-amine derivatives has been developed through the reaction of easily available aromatic aldehydes, benzoyl cyanide and either 2-aminoimidazole-4,5-dicarbonitrile or 3-amino-1,2,4-triazole in pyridine under controlled microwave heating. The process is environmentally friendly, is operationally simple, with short reaction time and with high yields. |
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ISSN: | 2191-9542 2191-9550 2191-9550 |
DOI: | 10.1515/gps-2018-0093 |