Regulation of cell growth and death by Epstein-Barr virus

• Published in: Microbes and Infection Vol. 2; no. 1; pp. 77 - 84
• Main Authors: Wensing, Barbara, Farrell, Paul J.
• Format: Book Review Journal Article
• Language: English
• Published: Lausanne Elsevier SAS 2000; Amsterdam Elsevier; Paris
• Subjects: Animals; apoptosis; Biological and medical sciences; Burkitt Lymphoma - physiopathology; Burkitt Lymphoma - virology; Burkitt's lymphoma; Cell Death; Cell Division; Chick Embryo; Epstein-Barr virus; Fundamental and applied biological sciences. Psychology; Gene Expression Regulation, Viral; Herpesvirus 4, Human - genetics; Herpesvirus 4, Human - physiology; Hodgkin Disease - physiopathology; Hodgkin Disease - virology; Humans; Microbiology; nasopharyngeal carcinoma; Nasopharyngeal Neoplasms - physiopathology; Nasopharyngeal Neoplasms - virology; NF-κB; Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains; Virology; NF-κB; apoptosis; nasopharyngeal carcinoma; Epstein-Barr virus; Burkitt's lymphoma; Gammaherpesvirinae; Cell proliferation; Herpesviridae; Epstein Barr virus; Review; Gene expression; Host virus relation; Virus; Regulation(control); Cell death; Infected cell; Transcription factor NFκB; Apoptosis
• ISSN: 1286-4579; 1769-714X
• DOI: 10.1016/S1286-4579(00)00282-3

Epstein-Barr virus (EBV) efficiently induces growth of human B cells and prevents cell death. Considerable progress has been made in understanding these processes, the role of EBV in human cancer cells and the relationship of viral gene expression to virus persistence and cancer.