Telomerase Activity in Benign and Malignant Breast Lesions: a Pilot Prospective Study on Fine-Needle Aspirates
Villa et al prospectively assessed the diagnostic accuracy of findings of telomerase activity in a consecutive series of fine-needle aspirates from 116 solid breast lesions that were subsequently submitted for histologic examination.
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Published in | JNCI : Journal of the National Cancer Institute Vol. 90; no. 7; pp. 537 - 539 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Cary, NC
Oxford University Press
01.04.1998
Oxford Publishing Limited (England) |
Subjects | |
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Abstract | Villa et al prospectively assessed the diagnostic accuracy of findings of telomerase activity in a consecutive series of fine-needle aspirates from 116 solid breast lesions that were subsequently submitted for histologic examination. |
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AbstractList | Villa et al prospectively assessed the diagnostic accuracy of findings of telomerase activity in a consecutive series of fine-needle aspirates from 116 solid breast lesions that were subsequently submitted for histologic examination. |
Author | Daidone, Maria Grazia Zaffaroni, Nadia Folini, Marco Silvestrini, Rosella Martelli, Gabriele Villa, Raffaella Palo, Giuseppe De |
Author_xml | – sequence: 1 givenname: Raffaella surname: Villa fullname: Villa, Raffaella organization: Oncologia Sperimentale C, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Milan, Italy, Italy – sequence: 2 givenname: Nadia surname: Zaffaroni fullname: Zaffaroni, Nadia organization: Oncologia Sperimentale C, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Milan, Italy, Italy – sequence: 3 givenname: Marco surname: Folini fullname: Folini, Marco organization: Oncologia Sperimentale C, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Milan, Italy, Italy – sequence: 4 givenname: Maria Grazia surname: Daidone fullname: Daidone, Maria Grazia organization: Oncologia Sperimentale C, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Milan, Italy, Italy – sequence: 5 givenname: Rosella surname: Silvestrini fullname: Silvestrini, Rosella organization: Oncologia Sperimentale C, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Milan, Italy, Italy – sequence: 6 givenname: Gabriele surname: Martelli fullname: Martelli, Gabriele organization: Oncologia Sperimentale C, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Milan, Italy, Italy – sequence: 7 givenname: Giuseppe De surname: Palo fullname: Palo, Giuseppe De organization: Oncologia Sperimentale C, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Milan, Italy, Italy |
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Cites_doi | 10.1093/jnci/88.16.1095 10.1093/jnci/88.2.116 10.1016/S0959-8049(97)00062-2 10.1126/science.7605428 10.1002/(SICI)1097-0215(19960822)69:4<301::AID-IJC11>3.0.CO;2-8 10.1093/jnci/89.24.1874 10.1002/(SICI)1096-9896(199709)183:1<57::AID-PATH1114>3.0.CO;2-4 10.1002/1097-0142(19930415)71:8<2522::AID-CNCR2820710815>3.0.CO;2-7 10.1093/jnci/87.12.884 |
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Keywords | Human Malignant tumor Experimental study Gene expression Telomere Differential diagnostic Mammary gland diseases Enzymatic activity Decision aid Female Mammary gland Benign neoplasm Comparative study |
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Notes | istex:42193CEC60B4773F611D20798E8CA1FFF3BEB269 ark:/67375/HXZ-JNFBJ8GC-R Supported by grants from the Associazione Italiana per la Ricerca sul Cancro and the Italian National Research Council (grant no. 97.00490. CT04). Correspondence to: Rosella Silvestrini, Ph.D., Oncologia Sperimentale C, Istituto Nazionale per lo Studio e la Cura dei Tumori, Via Venezian 1, 20133 Milan, Italy. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
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References | Avilion ( key 20170702061727_bib3) 1996; 56 Rhyu ( key 20170702061727_bib1) 1995; 87 Hiyama ( key 20170702061727_bib5) 1996; 88 Sugino ( key 20170702061727_bib6) 1996; 69 Sugino ( key 20170702061727_bib8) 1997; 183 Shay ( key 20170702061727_bib7) 1997; 33 Martelli ( key 20170702061727_bib9) 1993; 71 Tsao ( key 20170702061727_bib10) 1997; 3 Kim ( key 20170702061727_bib2) 1994; 266 Clark ( key 20170702061727_bib4) 1997; 89 Morin ( key 20170702061727_bib11) 1996; 88 |
References_xml | – volume: 88 start-page: 1095 year: 1996 ident: key 20170702061727_bib11 article-title: Telomere integrity and cancer publication-title: J Natl Cancer Inst doi: 10.1093/jnci/88.16.1095 contributor: fullname: Morin – volume: 88 start-page: 116 year: 1996 ident: key 20170702061727_bib5 article-title: Telomerase activity in human breast tumors publication-title: J Natl Cancer Inst doi: 10.1093/jnci/88.2.116 contributor: fullname: Hiyama – volume: 33 start-page: 787 year: 1997 ident: key 20170702061727_bib7 article-title: A survey of telomerase activity in human cancer publication-title: Eur J Cancer doi: 10.1016/S0959-8049(97)00062-2 contributor: fullname: Shay – volume: 266 start-page: 2011 year: 1994 ident: key 20170702061727_bib2 article-title: Specific association of human telomerase activity with immortal cells and cancer publication-title: Science doi: 10.1126/science.7605428 contributor: fullname: Kim – volume: 69 start-page: 301 year: 1996 ident: key 20170702061727_bib6 article-title: Telomerase activity in human breast cancer and benign breast lesions: diagnostic applications in clinical specimens, including fine needle aspirates publication-title: Int J Cancer doi: 10.1002/(SICI)1097-0215(19960822)69:4<301::AID-IJC11>3.0.CO;2-8 contributor: fullname: Sugino – volume: 3 start-page: 627 year: 1997 ident: key 20170702061727_bib10 article-title: Telomerase activity in normal and neoplastic breast publication-title: Clin Cancer Res contributor: fullname: Tsao – volume: 56 start-page: 645 year: 1996 ident: key 20170702061727_bib3 article-title: Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues publication-title: Cancer Res contributor: fullname: Avilion – volume: 89 start-page: 1874 year: 1997 ident: key 20170702061727_bib4 article-title: Telomerase activity and survival of patients with node-positive breast cancer publication-title: J Natl Cancer Inst doi: 10.1093/jnci/89.24.1874 contributor: fullname: Clark – volume: 183 start-page: 57 year: 1997 ident: key 20170702061727_bib8 article-title: Telomerase activity and its inhibition in benign and malignant breast lesions publication-title: J Pathol doi: 10.1002/(SICI)1096-9896(199709)183:1<57::AID-PATH1114>3.0.CO;2-4 contributor: fullname: Sugino – volume: 71 start-page: 2522 year: 1993 ident: key 20170702061727_bib9 article-title: Combined analysis of ploidy and cell kinetics on fine-needle aspirates from breast tumors publication-title: Cancer doi: 10.1002/1097-0142(19930415)71:8<2522::AID-CNCR2820710815>3.0.CO;2-7 contributor: fullname: Martelli – volume: 87 start-page: 884 year: 1995 ident: key 20170702061727_bib1 article-title: Telomeres, telomerase, and immortality publication-title: J Natl Cancer Inst doi: 10.1093/jnci/87.12.884 contributor: fullname: Rhyu |
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SubjectTerms | Adult Aged Aged, 80 and over Biological and medical sciences Biopsy, Needle Breast cancer Breast Diseases - enzymology Breast Neoplasms - enzymology Carcinoma - enzymology Enzymes Female Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical research Medical sciences Middle Aged Pilot Projects Polymerase Chain Reaction - methods Prospective Studies Repetitive Sequences, Nucleic Acid Sensitivity and Specificity Telomerase - metabolism Tumors |
Title | Telomerase Activity in Benign and Malignant Breast Lesions: a Pilot Prospective Study on Fine-Needle Aspirates |
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