Colonic adenocarcinoma in a 13-year-old with cystic fibrosis

• Published in: Journal of pediatric surgery Vol. 42; no. 10; pp. e1 - e3
• Main Authors: Ibele, Anna R, Koplin, Stephanie A, Slaughenhoupt, Bruce L, Kryger, John V, Friedl, Andreas, Lund, Dennis P
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2007
• Subjects: Adenocarcinoma - complications; Adenocarcinoma - drug therapy; Adenocarcinoma - surgery; Adolescent; Air; Anastomosis, Surgical; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Cecal Neoplasms - complications; Cecal Neoplasms - diagnostic imaging; Cecal Neoplasms - drug therapy; Colectomy; Combined Modality Therapy; Cystic Fibrosis - complications; Fluorouracil - administration & dosage; Humans; Intestinal Fistula - etiology; Intestinal Fistula - surgery; Intestinal Fistula - urine; Leucovorin - administration & dosage; Male; Organoplatinum Compounds - administration & dosage; Pediatrics; Surgery; Ultrasonography; Urinary Bladder Fistula - etiology; Urinary Bladder Fistula - surgery; Urinary Bladder Fistula - urine; Urine; Pneumaturia; Cystic fibrosis; Malignancy; Colon cancer; Enterovesical fistula
• ISSN: 0022-3468; 1531-5037
• DOI: 10.1016/j.jpedsurg.2007.07.024

Abstract The increase in longevity among patients with cystic fibrosis has brought to light comorbidities associated with the disease that are less acutely fatal than its pulmonary manifestations. Modern retrospective analysis has demonstrated an increased risk of gastrointestinal malignancy in patients with cystic fibrosis, with a marked elevation in malignancy rates among patients in their 20s and 30s. Here we report a case of colonic adenocarcinoma presenting as pneumaturia in a 13-year-old patient with cystic fibrosis.