Cytotoxic phenylethanol glycosides from Psidium guaijava seeds

• Published in: Phytochemistry (Oxford) Vol. 65; no. 14; pp. 2091 - 2093
• Main Authors: Salib, Josline Y., Michael, Helana N.
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 01.07.2004; Elsevier
• Subjects: Animals; anticarcinogenic activity; Biochemistry & Molecular Biology; Biological and medical sciences; Cell Line, Tumor; cell lines; Chemical constitution; chemical structure; cytotoxicity; Female; Fundamental and applied biological sciences. Psychology; General pharmacology; glycosides; Glycosides - chemistry; Glycosides - isolation & purification; human health; Humans; Life Sciences & Biomedicine; Magnetic Resonance Spectroscopy; Medical sciences; medicinal plants; medicinal properties; Mice; Myrtaceae; NMR spectroscopy; Pharmacognosy. Homeopathy. Health food; Pharmacological activity; Pharmacology. Drug treatments; Phenylethanoid glycosides; phenylethanol glycosides; phytochemicals; Plant physiology and development; Plant Sciences; Psidium - chemistry; Psidium guaijava; Psidium guajava; Science & Technology; Seeds; Seeds - chemistry; spectral analysis; Ultraviolet Rays; Egypt; Myrtaceae; Seeds; Pharmacological activity; NMR spectroscopy; Psidium guaijava; Phenylethanoid glycosides; phenylethanoid glycosides; pharmacological activity; seeds; Dicotyledones; Angiospermae; Isolation; Spermatophyta; Glycoside; Flavonoid
• ISSN: 0031-9422; 1873-3700
• DOI: 10.1016/j.phytochem.2004.06.009

Phytochemical investigations of the acetone extract of Psidium guaijava seeds has led to the isolation of two new phenylethanoid glycosides ( 1 and 2) and their investigation for their pharmacological activity. Phytochemical investigations of the acetone extract of Psidium guaijava seeds has led to the isolation of five known flavonoid glycosides, two phenolic glycosides and two new phenylethanoid glycosides which have been identified as 1- O-3,4-dimethoxy-phenylethyl-4- O-3,4-dimethoxy cinnamoyl-6- O-cinnamoyl-β- d-glucopyranose and 1- O-3,4-dimethoxyphenylethyl-4- O-3,4-dimethoxy cinnamoyl-β- d-glucopyranose, on the basis of chemical, physical and spectroscopic methods of analysis.