Composition and antifungal activity of the essential oil of Seseli annuum wild-growing in Serbia

• Published in: Fitoterapia Vol. 78; no. 4; pp. 319 - 322
• Main Authors: Milosavljević, Slobodan, Tešević, Vele, Vučković, Ivan, Jadranin, Milka, Vajs, Vlatka, Soković, Marina, Janaćković, Peđa, Jovanović, Anka
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.06.2007; Elsevier
• Subjects: Antifungal activity; Antifungal Agents - administration & dosage; Antifungal Agents - chemistry; Antifungal Agents - pharmacology; Antifungal Agents - therapeutic use; Apiaceae; Biological and medical sciences; Essential oil; General pharmacology; Germacrene D; Humans; Medical sciences; Medicine, Traditional; Microbial Sensitivity Tests; Mitosporic Fungi - drug effects; Pharmacognosy. Homeopathy. Health food; Pharmacology. Drug treatments; Phytotherapy; Plant Components, Aerial; Plant Oils - administration & dosage; Plant Oils - chemistry; Plant Oils - pharmacology; Plant Oils - therapeutic use; Seseli; Seseli annuum; Yugoslavia; Serbia; Europe; Yugoslavia; Antifungal activity; Essential oil; Seseli annuum; Germacrene D; Terpenoid; Pharmacognosy; Medicinal plant; Antifungal agent; Dicotyledones; Sesquiterpenes; Angiospermae; Plant origin; Spermatophyta; Umbelliferae
• ISSN: 0367-326X
• DOI: 10.1016/j.fitote.2007.03.014

The essential oil from the aerial parts of Seseli annuum, wild-growing in Serbia, was obtained by hydrodistillation and analyzed using GC and GC/MS. A total of 43 components were identified representing 96.5% of S. annuum oil. The most abundant compounds were germacrene D (29.8%), sabinene (10.3%), β-ocimene Z (9.8%) and limonene (8.6%). The essential oil showed antifungal activity against fifteen fungi with MICs between 12.5 to 50 μl/ml.