Facile Preparation of Water-Soluble and Cytocompatible Small-Sized Chitosan-Polydopamine Nanoparticles

In this paper, a kind of novel water-soluble chitosan-polydopamine （CHT-PDA） nanoparticles with a hydrody- namic diameter （Dh） around 10 nm were reported by the combination of self-polymerization of PDA and electro- static complexation between PDA and CHT in water/DMSO （W/D） mixture at the molar fra...

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Bibliographic Details
Published inChinese journal of chemistry Vol. 35; no. 6; pp. 931 - 937
Main Authors Ni, Yunzhou, Chen, Feng, Shi, Leilei, Tong, Gangsheng, Wang, Jie, Li, Huimei, Yu, Chunyang, Zhou, Yongfeng
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag GmbH & Co. KGaA 01.06.2017
Wiley Subscription Services, Inc
Subjects
Assaying
Biocompatibility
Chitosan
Complexation
Light transmittance
MTT比色法
Nanoparticles
polydopamine
Polymerization
Stellar mass
Sun
Transmittance
UV‐screen
visible‐light transmittance
二甲基亚砜
制备方法
可见光透过率
多巴胺
水溶性壳聚糖
纳米粒子
细胞相容性
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Summary:In this paper, a kind of novel water-soluble chitosan-polydopamine （CHT-PDA） nanoparticles with a hydrody- namic diameter （Dh） around 10 nm were reported by the combination of self-polymerization of PDA and electro- static complexation between PDA and CHT in water/DMSO （W/D） mixture at the molar fraction of DMSO （XDMSO =0.37）. The preparation method was efficient with a yield of 98% around. The as-prepared water-soluble CHT-PDA nanoparticles exhibited effective UV-screen ability, enhanced visible-light transmittance and good cyto- compatibility via MTT assay, which might be used in transparent formulation for UV protection usage, especially in biological field including sun care application.
Bibliography:chitosan, polydopamine, nanoparticles, UV-screen, visible-light transmittance
31-1547/O6
In this paper, a kind of novel water-soluble chitosan-polydopamine （CHT-PDA） nanoparticles with a hydrody- namic diameter （Dh） around 10 nm were reported by the combination of self-polymerization of PDA and electro- static complexation between PDA and CHT in water/DMSO （W/D） mixture at the molar fraction of DMSO （XDMSO =0.37）. The preparation method was efficient with a yield of 98% around. The as-prepared water-soluble CHT-PDA nanoparticles exhibited effective UV-screen ability, enhanced visible-light transmittance and good cyto- compatibility via MTT assay, which might be used in transparent formulation for UV protection usage, especially in biological field including sun care application.
ISSN:1001-604X
1614-7065
DOI:10.1002/cjoc.201600765