A Novel Protocol for the Regioselective Bromination of Primary Alcohols in Unprotected Carbohydrates or Glycosides

The regioselective and efficient bromination of primary hydroxyl groups in unprotected carbohydrates or glycosides is successfully achieved by using （chloro-phenylthio-methylene）dimethylammoniumchloride （CPMA） in the presence of tetrabutylammonium bromide （TBAB） in dry DMF.

Saved in:
Bibliographic Details
Published inChinese journal of chemistry Vol. 30; no. 7; pp. 1429 - 1432
Main Author 薛伟华 张立芬
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag 01.07.2012
WILEY‐VCH Verlag
Wiley
Wiley Subscription Services, Inc
Subjects
bromide
Carbohydrates
Chemistry
Chemistry, Multidisciplinary
CPMA
free sugars
glycosides
Physical Sciences
regioselective
Science & Technology
TBAB
伯醇
保护
区域选择性
协议
四丁基溴化铵
碳水化合物
苷
METALLOCYCLODEXTRINS
bromide
TRIPHENYLPHOSPHINE
regioselective
glycosides
CYCLOMALTOOLIGOSACCHARIDES
AQUEOUS-SOLUTION
BETA-CYCLODEXTRIN
CHEMISTRY
6(A)-(3-AMINOPROPYLAMINO)-6(A)-DEOXY-BETA-CYCLODEXTRIN
HOMOGENEOUS CONDITIONS
DERIVATIVES
COMPLEXATION
CPMA
free sugars
Online AccessGet full text

Cover

More Information
Summary:The regioselective and efficient bromination of primary hydroxyl groups in unprotected carbohydrates or glycosides is successfully achieved by using （chloro-phenylthio-methylene）dimethylammoniumchloride （CPMA） in the presence of tetrabutylammonium bromide （TBAB） in dry DMF.
Bibliography:regioselective, bromide, CPMA, free sugars, glycosides
The regioselective and efficient bromination of primary hydroxyl groups in unprotected carbohydrates or glycosides is successfully achieved by using （chloro-phenylthio-methylene）dimethylammoniumchloride （CPMA） in the presence of tetrabutylammonium bromide （TBAB） in dry DMF.
31-1547/O6
the Fundamental Research Funds for the Lanzhou University - No. lzujbky-2011-136
ArticleID:CJOC201200211
ark:/67375/WNG-39CFCMHW-6
the Natural Science Foundation for Young Scientists in Gansu Province, China - No. 1107RJYA038
istex:331DE711CFF00D4BE5E6EBB2B7336AF7CF5BD28E
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ISSN:1001-604X
1614-7065
DOI:10.1002/cjoc.201200211