Disseminated histoplasmosis in an infant with acquired immunodeficiency syndrome

Disseminated histoplasmoids has been recognized as a serious opportunistic infection in patients with acquired immunodeficiency syndrome (AIDS). However, cases reported in the literature have been predominantly in adult patients. Here we report an infant with AIDS who presented with fever, cough, rh...

Full description

Saved in:
Bibliographic Details
Published inThe Journal of infection Vol. 37; no. 3; pp. 298 - 301
Main Authors Wang, H., Abrahams, C., Hart, J., Johnson, D., Wollmann, R.L.
Format Journal Article
LanguageEnglish
Published Kidlington Elsevier Ltd 01.11.1998
Elsevier
Subjects
Acquired Immunodeficiency Syndrome - complications
AIDS/HIV
Biological and medical sciences
Fatal Outcome
Histoplasma - isolation & purification
Histoplasmosis - complications
Histoplasmosis - pathology
Human immunodeficiency virus
Human viral diseases
Humans
Infant
Infectious diseases
Male
Medical sciences
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Human
Immunopathology
Opportunistic infection
Histoplasmosis
Mycosis
Infant
AIDS
Immune deficiency
Infection
Case study
Viral disease
Complication
Disseminated
Online AccessGet full text

Cover

More Information
Summary:Disseminated histoplasmoids has been recognized as a serious opportunistic infection in patients with acquired immunodeficiency syndrome (AIDS). However, cases reported in the literature have been predominantly in adult patients. Here we report an infant with AIDS who presented with fever, cough, rhinorrhea, hepatosplenomegaly, pancytopenia and coagulopathy, and died of respiratory failure. Autopsy revealed disseminated histoplasmosis involving multiple organs including lungs, intestines, liver, spleen, bone marrow, lymph nodes, kidneys, and meninges. The diagnosis was established based on histomorphology and confirmed by blood culture.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Case Study-2
ObjectType-Feature-4
ObjectType-Report-1
ObjectType-Article-3
ISSN:0163-4453
1532-2742
DOI:10.1016/S0163-4453(98)92293-9