Cuvette-based microfluidic device integrated with nanostructures for measuring dual Localized Surface Plasmon Resonance (LSPR) signals

A spectrophotometer that uses a localized surface plasmon resonance phenomenon is a powerful measurement tool in the biotechnology and bioanalysis fields. We propose a novel cuvette design type that can be used for universal spectrophotometers. The novel cuvette design needs a few l reagent for meas...

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Bibliographic Details
Published inReview of scientific instruments Vol. 89; no. 11; p. 113107
Main Authors Jung, Daekyeong, Ahn, Junhyoung, Jo, Narae, Lee, Jaejong, Shin, Young-Beom, Lim, Hyungjun
Format Journal Article
LanguageEnglish
Published United States 01.11.2018
Subjects
Equipment Design
Lab-On-A-Chip Devices
Nanostructures
Surface Plasmon Resonance - instrumentation
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Summary:A spectrophotometer that uses a localized surface plasmon resonance phenomenon is a powerful measurement tool in the biotechnology and bioanalysis fields. We propose a novel cuvette design type that can be used for universal spectrophotometers. The novel cuvette design needs a few l reagent for measuring, and also two chips for measurement can be loaded and measured at the same time. A new cuvette can easily be used several times because of sample chips to be loaded and unloaded since they are mechanically mounted by screws. Therefore, it can offer advantages to users in terms of cost and time. We verify its possibility for use in the biotechnology and bioanalysis fields by a signal enhancement and dual signal detection.
ISSN:1089-7623
DOI:10.1063/1.5030051