Effect of dexmedetomidine on the median effective concentration of ropivacaine for postoperative analgesia in transversus abdominis plane block: an up-down sequential allocation study

• Published in: Frontiers in medicine Vol. 12; p. 1491849
• Main Authors: Ye, Qin, Xu, Hongchun, Liu, Xiao, Wang, Xujiao, Wang, Fangjun
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 28.04.2025
• Subjects: dexmedetomidine; EC50; Medicine; postoperative pain; ropivacaine; transversus abdominis plane block; ropivacaine; EC50; dexmedetomidine; transversus abdominis plane block; postoperative pain

This study aimed to observe the effect of dexmedetomidine on the median effective concentration (EC ) of ropivacaine for postoperative analgesia in ultrasound-guided transversus abdominis plane block. Patients undergoing elective laparoscopic cholecystectomy were randomly divided into the RD group a...