Expression of Simian Immunodeficiency Virus nef in Immune Cells of Transgenic Mice Leads to a Severe AIDS-Like Disease

• Published in: Journal of Virology Vol. 76; no. 8; pp. 3981 - 3995
• Main Authors: Simard, Marie-Chantal, Chrobak, Pavel, Kay, Denis G, Hanna, Zaher, Jothy, Serge, Jolicoeur, Paul
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.04.2002
• Subjects: Acquired Immunodeficiency Syndrome - etiology; Acquired Immunodeficiency Syndrome - pathology; Acquired Immunodeficiency Syndrome - physiopathology; Animals; CD4-Positive T-Lymphocytes - immunology; CD4-Positive T-Lymphocytes - metabolism; CD8-Positive T-Lymphocytes - immunology; Disease Models, Animal; Female; Gene Products, nef - genetics; Gene Products, nef - metabolism; Genes, nef; Humans; Mice; Mice, Transgenic; nef Gene Products, Human Immunodeficiency Virus; Pathogenesis and Immunity; Simian Immunodeficiency Virus - genetics; Simian Immunodeficiency Virus - metabolism; Simian Immunodeficiency Virus - pathogenicity
• ISSN: 0022-538X; 1098-5514
• DOI: 10.1128/JVI.76.8.3981-3995.2002

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