Ethical issues in neonatal research involving human subjects

Abstract Research involving critically ill neonates creates many ethical challenges. Neonatal clinical research has always been hard to perform, is very expensive, and may generate some unique ethical concerns. This article describes some examples of historical and modern controversies in neonatal r...

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Bibliographic Details
Published inSeminars in perinatology Vol. 40; no. 4; pp. 247 - 253
Main Author Fleischman, Alan R., MD
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.06.2016
Subjects
Biomedical Research - ethics
Clinical Trials as Topic
Critical Illness
Ethics Committees, Research
Ethics, Medical
Extracorporeal Membrane Oxygenation - ethics
Federal Government
federal regulations
Guidelines as Topic
Humans
Infant, Newborn
Infant, Newborn, Diseases - therapy
Informed Consent - ethics
Neonatal and Perinatal Medicine
neonatology
Neonatology - ethics
Neonatology - trends
Patient Selection - ethics
research ethics
United States
research ethics
neonatology
federal regulations
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Summary:Abstract Research involving critically ill neonates creates many ethical challenges. Neonatal clinical research has always been hard to perform, is very expensive, and may generate some unique ethical concerns. This article describes some examples of historical and modern controversies in neonatal research, discusses the justification for research involving such vulnerable and fragile patients, clarifies current federal regulations that govern research involving neonates, and suggests ways that clinical investigators can develop and implement ethically grounded human subjects research.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0146-0005
1558-075X
DOI:10.1053/j.semperi.2015.12.014