Articaine and Lidocaine Mandibular Buccal Infiltration Anesthesia: A Prospective Randomized Double-Blind Cross-Over Study

• Published in: Journal of endodontics Vol. 32; no. 4; pp. 296 - 298
• Main Authors: Kanaa, Mohammad Dib, Whitworth, John Martin, Corbett, Ian Porter, Meechan, John Gerard
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2006
• Subjects: Administration, Buccal; Adult; Anesthesia, Dental - methods; Anesthesia, Local - methods; Anesthetics, Local - administration & dosage; Articaine; Carticaine - administration & dosage; Chi-Square Distribution; Cross-Over Studies; Dental Pulp Test; Dentistry; Double-Blind Method; Female; Humans; lidocaine; Lidocaine - administration & dosage; local anesthesia; lower molar teeth; Male; Mandibular Nerve; Molar; Prospective Studies; Statistics, Nonparametric; Articaine; local anesthesia; lower molar teeth; lidocaine
• ISSN: 0099-2399; 1878-3554
• DOI: 10.1016/j.joen.2005.09.016

This randomized crossover double-blind trial compared the efficacy of buccal infiltration with 4% articaine and 2% lidocaine (both with 1:100,000 epinephrine) in securing mandibular first molar pulp anesthesia. Injections were given at least 1 week apart in 31 healthy adult volunteers. Electronic pulp testing was undertaken at baseline and at 2 minute intervals until 30 minutes postinjection. A successful outcome was recorded in the absence of pulp sensation on two consecutive maximal pulp tester stimulations (80 μA). 64.5% of articaine and 38.7% of lidocaine infiltrations were successful (p = 0.008). Articaine infiltration produced significantly more episodes of no response to maximum stimulation in first molars than lidocaine (236 and 129, respectively, p < 0.001). Mandibular buccal infiltration is more effective with 4% articaine with epinephrine compared to 2% lidocaine with epinephrine. Both injections were associated with mild discomfort.