Epigenetic regulation of macrophage activation in chronic obstructive pulmonary disease

• Published in: Frontiers in immunology Vol. 15; p. 1445372
• Main Authors: Zhang, Feng, Cui, Yachao, Zhang, Tiejun, Yin, Wenguang
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 14.08.2024
• Subjects: Animals; COPD; DNA Methylation; Epigenesis, Genetic; epigenetic regulation; histone modifications; Humans; Immunology; macrophage; Macrophage Activation - genetics; Macrophage Activation - immunology; Macrophages - immunology; Macrophages - metabolism; Pulmonary Disease, Chronic Obstructive - genetics; Pulmonary Disease, Chronic Obstructive - immunology; DNA methylation; macrophage; histone modifications; epigenetic regulation; COPD
• ISSN: 1664-3224; 1664-3224
• DOI: 10.3389/fimmu.2024.1445372

Macrophages in the innate immune system play a vital role in various lung diseases such as asthma, chronic obstructive pulmonary disease (COPD), acute lung injury and pulmonary fibrosis. Macrophages involved in the process of immunity need to go through a process of activation, including changes in...