Complete genome sequence of serotype 3 Streptococcus suis INT-01, isolated from a domestic pig in Korea

• Published in: Journal of animal science and technology Vol. 63; no. 3; pp. 662 - 665
• Main Authors: Park, Seon Young, Kim, In Hwang, Yu, Hyun Jin, Paik, Hyoung Rok, Son, Jee Soo, Kim, Ji Hyung
• Format: Journal Article
• Language: English
• Published: Korean Society of Animal Sciences and Technology 01.05.2021; 한국축산학회
• Subjects: control strategy; genotype; pathogen; streptococcus suis; swine industry; 축산학
• ISSN: 2672-0191; 2055-0391; 2093-6281
• DOI: 10.5187/jast.2021.e47

Streptococcus suis is a major pig pathogen causing severe economic losses to the swine industry. This study aimed to analyze the genome of S. suis strain INT-01 isolated from a domestic pig in Korea. We found that the genome of strain INT-01 contains 2,092,054 bp, with a guanine (G) + cytosine (C) content of 41.3%, and the capsular polysaccharide synthesis locus of this strain is almost identical to that of serotype 3 S. suis strain 4961 isolated from China, suggesting that these isolates can be classified as serotype 3. Genomic analyses revealed that strain INT-01 is an extracellular protein factor ( epf ) − / muraminidase-released protein ( mrp ) + / suilysin ( sly ) − S. suis , which is the most prevalent genotype in Korea, and several virulence-related genes associated with the pathogenicity of S. suis were also detected. The genomic information of strain INT-01 may provide important insights into the development of control strategies against S. suis infections in Korea.