Risk Factor Analysis for Breast Cellulitis Complicating Breast Conservation Therapy

• Published in: Clinical infectious diseases Vol. 31; no. 3; pp. 654 - 659
• Main Authors: Brewer, Valerie H., Hahn, Kevin A., Rohrbach, Barton W., Bell, John L., Baddour, Larry M.
• Format: Journal Article
• Language: English
• Published: Chicago, IL The University of Chicago Press 01.09.2000; University of Chicago Press
• Subjects: Adult; Aged; Biological and medical sciences; Breast - pathology; Breast Diseases - complications; Breast Diseases - diagnosis; Breast Diseases - diagnostic imaging; Breast Neoplasms - complications; Breast Neoplasms - surgery; Breasts; Case-Control Studies; Cellulitis; Cellulitis - complications; Cellulitis - diagnosis; Cellulitis - diagnostic imaging; Ecchymosis; Female; Gynecology. Andrology. Obstetrics; Hematoma; Humans; Infections; Lymphedema; Major Articles; Mammary gland diseases; Mammography; Mastectomy, Segmental; Medical sciences; Middle Aged; Postmenopause; Predisposing factors; Risk Factors; Segmental mastectomy; Seroma; Statistics as Topic; Time Factors; Tumors; Ultrasonography; Human; Postoperative; Skin disease; Malignant tumor; Cellulitis; Mammary gland diseases; Conservative surgery; Treatment; Risk factor; Complication; Female; Adipose tissue disorders; Mammary gland
• ISSN: 1058-4838; 1537-6591
• DOI: 10.1086/314021

Women who undergo breast conservation therapy for early-stage breast cancer can develop breast cellulitis, a complication for which risk factors are undefined. A matched case-control investigation was conducted to identify risk factors for the development of breast cellulitis among patients who have undergone breast conservation therapy. Patients comprised 17 patients with cases of breast cellulitis diagnosed after partial mastectomies that had been performed from 1992 through 1997 and 34 control patients who were matched to case-patients by date of breast lumpectomy and by primary surgeon. Statistical analyses indicated the following factors were associated with breast cellulitis: drainage of a hematoma (P = .010); postoperative ecchymosis (P = .021); lymphedema (odds ratio [OR], 10.154; 95% confidence interval [CI], 1.348-208.860); resected breast tissue volume (OR, 1.456; 95% CI, 1.035-2.168); and previous number of breast seroma aspirations (OR, 3.445; 95% CI, 1.036-19.771). This is the first matched case-control study to identify risk factors for the development of breast cellulitis after breast conservation therapy.