Dopamine effect on 20-hydroxyecdysone level is mediated by juvenile hormone in Drosophila females

• Published in: Doklady. Biochemistry and biophysics Vol. 446; no. 1; pp. 263 - 265
• Main Authors: Rauschenbach, I. Yu, Laukhina, O. V., Alekseev, A. A., Adonyeva, N. V., Bogomolova, E. V., Gruntenko, N. E.
• Format: Journal Article
• Language: English
• Published: Dordrecht SP MAIK Nauka/Interperiodica 01.09.2012; Springer Nature B.V
• Subjects: Animals; Biochemistry; Biological and Medical Physics; Biomedical and Life Sciences; Biophysics; Biophysics and Molecular Biology; Corpora Allata - metabolism; Dopamine; Dopamine - metabolism; Drosophila melanogaster - metabolism; Ecdysterone - metabolism; Female; Females; Gene expression; Gene Expression Regulation - physiology; Immunohistochemistry; Insects; Juvenile Hormones - biosynthesis; Life Sciences; DOKLADY Biochemistry; Ecdysone; Hybrid Female; Yolk Protein; Juvenile Hormone
• ISSN: 1607-6729; 1608-3091
• DOI: 10.1134/S1607672912050171

This study verified the hypothesis that dopamine regulates the 20E titer indirectly through the metabolism of uvenile hormone. The study used two approaches: (1) immunohistochemical analysis of the ovaries of young Drosophila females using antibodies against D1 like receptors and (2) assessment of the level of 20E in Drosophila female with a reduced number of D2 like receptors in CA (earlier we showed that the synthesis of JH in these females is increased