Evaluation of endoscopic ultrasonography in colorectal villous lesions

• Published in: International journal of colorectal disease Vol. 18; no. 1; pp. 19 - 24
• Main Authors: KONISHI, Kazuo, AKITA, Yasushi, KANEKO, Kazuhiro, KURAHASHI, Toshinori, YAMAMOTO, Taikan, KUSAYANAGI, Satoshi, YOSHIKAWA, Nozomi, MIYASAKA, Nobuo, TAJIRI, Hisao, MITAMURA, Keiji
• Format: Journal Article
• Language: English
• Published: Heidelberg Springer 2003; Berlin Springer Nature B.V
• Subjects: Adenoma, Villous - diagnostic imaging; Adenoma, Villous - pathology; Adult; Aged; Aged, 80 and over; Biological and medical sciences; Colorectal Neoplasms - diagnostic imaging; Colorectal Neoplasms - pathology; Diagnosis, Differential; Digestive system. Abdomen; Endosonography; Female; Humans; Intestinal Mucosa - diagnostic imaging; Investigative techniques, diagnostic techniques (general aspects); Japan; Male; Medical sciences; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Predictive Value of Tests; Sensitivity and Specificity; Ultrasonic investigative techniques; Performance evaluation; Rectal disease; Carcinoma; Endosonography; Colorectal carcinoma; Intestinal disease; Selection criterion; Intestinal villi; Endoscopy; Colon; Vinous adenoma; Sonography; Human; Endoscopic surgery; Adenomatous polyp; Endoscopic ultrasonography; Surgical resection; Malignant tumor; Invasion; Colonic disease; Treatment; Endoscopic approach; Echography; Rectum; Digestive diseases; Colorectal polyp
• ISSN: 0179-1958; 1432-1262
• DOI: 10.1007/s00384-002-0423-6

The choice of therapeutic procedure for colorectal neoplasias depends largely on the depth of tumor invasion. This study examined the value of endoscopic ultrasonography (EUS) in determining whether local resection is applicable for colorectal villous lesions. We performed EUS on 125 colorectal neoplasias classified into two categories, villous ( n=35) and nonvillous lesions ( n=90), according to their colonoscopic morphological features. We compared the EUS and clinicopathological findings for each lesion. The overall accuracy of EUS-based evaluation of tumor invasion depth was 60% in villous lesions and 91% in nonvillous lesions. In villous lesions 37% were overstaged and 3% understaged, and in of nonvillous lesions 6% were overstaged and 3% understaged. In differentiating mucosal neoplasias (M)/submucosal cancers with slight invasion (SM-s) from non-M/SM-s, the values in villous and nonvillous lesions were, respectively: sensitivity 60% and 86%, specificity 100% and 99%, and accuracy 66% and 96%. Large (>/=20 mm wide, >/=5 mm high) or rectal villous lesions were more likely than nonvillous lesions to be misjudged with regard to the differentiation between M/SM-s and non-M/SM-s. It is difficult to determine the depth of invasion in villous lesions, especially large or rectal lesions, using only EUS. EUS-based evaluation alone cannot determine the appropriate treatment for colorectal villous lesions.