Efficacy of whole-body cryotherapy in the treatment of chronic low back pain: Quasi-experimental study
Single arm, quasi-experimental study design. To describe the effects of whole-body cryotherapy on pain, disability, and serum inflammatory markers in patients with chronic low back pain. A quasi-experimental trial was performed on adult patients between 18 and 65 years with chronic low back pain. Af...
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Published in | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association Vol. 28; no. 1; pp. 112 - 116 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Japan
Elsevier B.V
01.01.2023
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Subjects | |
Online Access | Get full text |
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Summary: | Single arm, quasi-experimental study design.
To describe the effects of whole-body cryotherapy on pain, disability, and serum inflammatory markers in patients with chronic low back pain.
A quasi-experimental trial was performed on adult patients between 18 and 65 years with chronic low back pain. After obtaining informed consent, participants underwent 20 sessions of whole-body cryotherapy (at −160 °C) during a 5-week time span. Patient reported pain and disability measures (Pain Numerical Rating Scale [PNRS], Oswestry Disability Index [OSI], and Roland Morris Questionnaire [RMQ]) were obtained at each of the twenty sessions. Blood samples were obtained to analyze serum inflammatory markers at baseline, 10th and 20th session.
Forty-one participants were included in the study. A significant decrease was observed between the initial and final PNRS, ODI, and RMQ scores (p < 0.001). A significant reduction in the PNRS was found after 4 sessions of whole-body cryotherapy (p < 0.001). We observed decreasing values of pro-inflammatory serum marker IL-2 (p = 0.046) and a significant increase in the anti-inflammatory serum marker IL-10 (p = 0.003). No adverse events were reported during the study.
Whole-body cryotherapy is an effective therapy for pain and disability treatment in chronic low back pain. It also produces changes in serum markers of inflammation, decreasing pro-inflammatory markers and increasing anti-inflammatory markers. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0949-2658 1436-2023 |
DOI: | 10.1016/j.jos.2021.10.006 |