Stem cell therapies: a new era in the treatment of multiple sclerosis

Multiple Sclerosis (MS) is an immune-mediated condition that persistently harms the central nervous system. While existing treatments can slow its course, a cure remains elusive. Stem cell therapy has gained attention as a promising approach, offering new perspectives with its regenerative and immun...

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Published inFrontiers in neurology Vol. 15; p. 1389697
Main Authors Wu, Lei, Lu, Jing, Lan, Tianye, Zhang, Dongmei, Xu, Hanying, Kang, Zezheng, Peng, Fang, Wang, Jian
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 09.05.2024
Subjects
induced pluripotent stem cells
multiple sclerosis
neural stem cells
Neurology
stem cell therapy
stem cell transplantation
induced pluripotent stem cells
neural stem cells
multiple sclerosis
stem cell therapy
stem cell transplantation
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Summary:Multiple Sclerosis (MS) is an immune-mediated condition that persistently harms the central nervous system. While existing treatments can slow its course, a cure remains elusive. Stem cell therapy has gained attention as a promising approach, offering new perspectives with its regenerative and immunomodulatory properties. This article reviews the application of stem cells in MS, encompassing various stem cell types, therapeutic potential mechanisms, preclinical explorations, clinical research advancements, safety profiles of clinical applications, as well as limitations and challenges, aiming to provide new insights into the treatment research for MS.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
Reviewed by: Ibrahim Nazih Kassis, Hadassah Medical Center, Israel
Edited by: Marija Mostarica-Stojkovic, University of Belgrade, Serbia
Sergej Tomić, Institute for the Application of Nuclear Energy (INEP), Serbia
ISSN:1664-2295
1664-2295
DOI:10.3389/fneur.2024.1389697