Public health implications of hazardous waste sites: Findings, assessment and research

In this paper we present an overview of the chemicals released from hazardous waste sites (HWS) and some of the mixtures of substances that have been released into environmental media. We describe how this information can be used to assess the public health hazard of releases of chemical mixtures fr...

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Bibliographic Details
Published inFood and chemical toxicology Vol. 34; no. 11; pp. 1131 - 1138
Main Authors De Rosa, C.T., Johnson, B.L., Fay, M., Hansen, H., Mumtaz, M.M.
Format Journal Article Conference Proceeding
LanguageEnglish
Published Oxford Elsevier Ltd 01.11.1996
New York, NY Elsevier Science
Subjects
Animals
Biological and medical sciences
Environmental Exposure
Environmental pollutants toxicology
General aspects
Hazardous Substances - adverse effects
Hazardous Substances - toxicity
Hazardous Waste - adverse effects
Humans
Medical sciences
Public Health - standards
Rats
Research Design - standards
Risk Assessment
Toxicology
United States
United States Environmental Protection Agency
United States
North America
America
National Institute of Environmental Health Sciences
National Priorities List
HWS
Comprehensive Environmental Response, Compensation and Liability Act
Hazardous Waste Sites
Agency for Toxic Substances and Disease Registry
NPL
CERCLA
Fiscal Year
FY
ATSDR
EPA
NIEHS
Environmental Protection Agency
OTA
Office of Technology Assessment
Human
Evaluation
Sanitary landfill
Toxicity
Chemical compound
Dangerous product
Risk
Wastes
Mixture
Public health
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Summary:In this paper we present an overview of the chemicals released from hazardous waste sites (HWS) and some of the mixtures of substances that have been released into environmental media. We describe how this information can be used to assess the public health hazard of releases of chemical mixtures from waste sites. Wherever possible, research on chemical mixtures should use chemical mixtures actually identified in, or representative of, mixtures in environmental media. A narrative, weight-of-evidence approach to characterize the toxicity of mixtures that incorporates mechanistic insights on chemical interactions is described. The utility of this information in the context of risk analysis and public health practice is discussed.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0278-6915
1873-6351
DOI:10.1016/S0278-6915(97)00084-7