The pharmacology and toxicology of the synthetic cathinone mephedrone (4-methylmethcathinone)

Mephedrone (4-methylmethcathinone) is a synthetic cathinone that is used as a recreational drug. It has been available since 2007 but its availability and use increased significantly during 2009 and 2010. In this review article we will summarize the available literature on the sources, availability,...

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Bibliographic Details
Published inDrug testing and analysis Vol. 3; no. 7-8; p. 454
Main Authors Dargan, Paul I, Sedefov, Roumen, Gallegos, Ana, Wood, David M
Format Journal Article
LanguageEnglish
Published England 01.07.2011
Subjects
Alkaloids - pharmacology
Alkaloids - poisoning
Alkaloids - toxicity
Animals
Designer Drugs - pharmacology
Designer Drugs - poisoning
Designer Drugs - toxicity
Humans
Methamphetamine - analogs & derivatives
Methamphetamine - pharmacology
Methamphetamine - poisoning
Methamphetamine - toxicity
Street Drugs - pharmacology
Street Drugs - poisoning
Street Drugs - toxicity
Substance-Related Disorders - diagnosis
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Summary:Mephedrone (4-methylmethcathinone) is a synthetic cathinone that is used as a recreational drug. It has been available since 2007 but its availability and use increased significantly during 2009 and 2010. In this review article we will summarize the available literature on the sources, availability, and prevalence of the use of mephedrone. We will also discuss the pharmacology of mephedrone, the patterns of acute toxicity associated with its use, the reports of fatalities associated with its use, and the potential for mephedrone dependence.
ISSN:1942-7611
DOI:10.1002/dta.312