Cognitive Behavioral Therapy for Insomnia in Alcohol‐Dependent Veterans: A Randomized, Controlled Pilot Study

• Published in: Alcoholism, clinical and experimental research Vol. 43; no. 6; pp. 1244 - 1253
• Main Authors: Chakravorty, Subhajit, Morales, Knashawn H., Arnedt, J. Todd, Perlis, Michael L., Oslin, David W., Findley, James C., Kranzler, Henry R.
• Format: Journal Article
• Language: English
• Published: England 01.06.2019
• Subjects: Alcoholism; Cognitive Therapy; Sleep Initiation and Maintenance Disorders; Veterans; Cognitive Therapy; Veterans; Sleep Initiation and Maintenance Disorders; Alcoholism
• ISSN: 0145-6008; 1530-0277
• DOI: 10.1111/acer.14030

Background Insomnia is highly prevalent in individuals recovering from alcohol dependence (AD) and increases their risk of relapse. Two studies evaluating cognitive behavior therapy for insomnia (CBT‐I) have demonstrated its efficacy in non‐Veterans recovering from AD. The aim of this study was to extend these findings in an 8‐week trial of CBT‐I in Veterans. Methods Veterans recovering from AD were randomly assigned to 8 weeks of treatment with CBT‐I (N = 11) or a Monitor‐Only (MO; N = 11) condition and were evaluated 3 (N = 21/22) and 6 months posttreatment (N = 18/22). The primary outcome measure was the Insomnia Severity Index (ISI) score. Secondary outcome measures were sleep diary measures, percent days abstinent (PDA), and scores on the Dysfunctional Beliefs and Attitudes About Sleep Scale (DBAS), Sleep Hygiene Index (SHI), Penn Alcohol Craving Scale (PACS), Quick Inventory of Depressive Symptoms (QIDS), State‐Trait Anxiety Inventory‐Trait (STAI‐T) scale, and Short Form 12‐item (SF‐12). Mixed‐effects regression models, adjusted for race, evaluated differences in outcomes between the groups over a 6‐month period (clinicaltrials.gov identifier = NCT01603381). Results Subjects were male, aged 54.5 (SD = 6.9) years, and had 26.4 (SD = 26.3) days of abstinence before their baseline evaluation. CBT‐I produced a significantly greater improvement in model‐based estimates than MO (mean change at 6 months compared to their baseline) for ISI, sleep latency from a daily sleep diary, DBAS mean score, and SHI total score. PDA and QIDS improved over time, but there was no difference between the groups. PACS, STAI‐T, or SF‐12 scale did not show any improvement from their baseline scores. Conclusions CBT‐I treatment demonstrated substantial efficacy in reducing insomnia, associated negative cognitions, and improving sleep hygiene in Veterans during early recovery, though it did not reduce drinking behavior. Insomnia is a commonly comorbid condition in alcohol dependence (AD). Cognitive Behavioral Therapy for Insomnia (CBT‐I) has demonstrated efficacy for insomnia in AD in the community. We extend these findings to Veterans (N = 24) with AD. We found that 8‐week CBT‐I treatment (N = 11), as compared to Monitor‐Only (MO, N = 11) arm, improved their insomnia scores, sleep latency, dysfunctional sleep‐related cognitions, and sleep hygiene over a 6‐month period without improving alcohol‐related outcomes. Thus, CBT‐I is efficacious in treating insomnia in AD during recovery.