A ratiometric fluorescent probe based on a BODIPY-DCDHF conjugate for the detection of hypochlorous acid in living cells

A colorimetric and ratiometric fluorescent probe consisting of a boron-dipyrromethene (BODIPY) dye conjugated with a 2-dicyanomethylene-3-cyano-2,5-dihydrofuran (DCDHF) group has been designed for the selective and sensitive detection of HOCl/OCl(-)via oxidative cleavage of an alkene linker between...

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Bibliographic Details
Published inAnalyst (London) Vol. 138; no. 12; pp. 3368 - 3371
Main Authors Park, Jeesook, Kim, Hyunjin, Choi, Yongdoo, Kim, Youngmi
Format Journal Article
LanguageEnglish
Published England 21.06.2013
Subjects
Animals
Boron Compounds - chemistry
Cell Line
Cell Survival
Cells - chemistry
Cells - cytology
Cleavage
Colorimetry
Conjugates
Dyes
Fluorescent Dyes - chemistry
Furans - chemistry
Hypochlorous Acid - analysis
Mice
Molecular Imaging - methods
Nitriles - chemistry
Olefins
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Summary:A colorimetric and ratiometric fluorescent probe consisting of a boron-dipyrromethene (BODIPY) dye conjugated with a 2-dicyanomethylene-3-cyano-2,5-dihydrofuran (DCDHF) group has been designed for the selective and sensitive detection of HOCl/OCl(-)via oxidative cleavage of an alkene linker between BODIPY and DCDHF.
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ISSN:0003-2654
1364-5528
DOI:10.1039/c3an36820c