Role of narrowband imaging in assessing endobronchial cryptococcosis

Endobronchial cryptococcosis can cause tracheobronchitis with granulomatous changes. In this patient under steroid therapy, bronchoscopic images revealed elevated white patchy lesion on the posterior longitudinal folds of the lower trachea. Bronchoscopy with narrowband imaging (NBI) revealed opaque...

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Bibliographic Details
Published inJournal of bronchology & interventional pulmonology Vol. 20; no. 3; p. 249
Main Authors Handa, Hiroshi, Kurimoto, Noriaki, Mineshita, Masamichi, Miyazawa, Teruomi
Format Journal Article
LanguageEnglish
Published United States 01.07.2013
Subjects
Aged
Biopsy
Bronchial Diseases - diagnosis
Bronchial Diseases - drug therapy
Bronchial Diseases - pathology
Bronchoscopy - methods
Cryptococcosis - diagnosis
Cryptococcosis - drug therapy
Cryptococcosis - pathology
Cryptococcus neoformans
Female
Fluconazole - therapeutic use
Humans
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Summary:Endobronchial cryptococcosis can cause tracheobronchitis with granulomatous changes. In this patient under steroid therapy, bronchoscopic images revealed elevated white patchy lesion on the posterior longitudinal folds of the lower trachea. Bronchoscopy with narrowband imaging (NBI) revealed opaque bronchial subepithelial vessels. Endobronchial biopsy confirmed Cryptococcus neoformans infection in the subepithelial layer. Following treatment with fluconazole, bronchoscopy with NBI revealed the disappearance of elevated lesion and regrowth of vessels of regular caliber. NBI might be useful to assess and follow-up endobronchial fungal infection and other inflammatory processes.
ISSN:1948-8270
DOI:10.1097/lbr.0b013e31829aaecb