Pupil dilation with intracameral 1% lidocaine during glaucoma filtering surgery

• Published in: American journal of ophthalmology Vol. 136; no. 1; pp. 201 - 203
• Main Authors: Lee, John J., Moster, Marlene R., Henderer, Jeffrey D., Membreno, Jaime H.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.07.2003; Elsevier; Elsevier Limited
• Subjects: African Americans; Anesthesia, Local; Anesthetics, Local - administration & dosage; Anterior Chamber - drug effects; Biological and medical sciences; Eye Color; Female; Glaucoma; Glaucoma - surgery; Glaucoma and intraocular pressure; Humans; Injections; Lidocaine - administration & dosage; Male; Medical sciences; Ophthalmology; Parapsychology; Pupil - drug effects; Retrospective Studies; Sex Factors; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the eye and orbit; Trabeculectomy; Human; Pupil; Eye disease; Dilatation; Glaucoma (eye); Surgery; Anterior chamber; Injection; Lidocaine; Biological activity
• ISSN: 0002-9394; 1879-1891
• DOI: 10.1016/S0002-9394(03)00150-8

To evaluate pupil dilation from intracameral injection of nonpreserved 1% lidocaine. Observational case series of 25 consecutive phakic trabeculectomies. Patients were evaluated in the operating room setting and given one drop of topical tetracaine preoperatively. Nonpreserved 1% lidocaine (0.1 cc) was injected intracameraly into the anterior chamber through a paracentesis site at the corneal limbus. Pupil diameter was measured after instillation of topical tetracaine, before injection of intracameral lidocaine. Postinjection measurements were made at 1, 3, and 5 minutes. The mean male pupil diameter was significantly greater than female dilation at every time point. The mean blue iris diameter was greater than brown at 1 and 3 minutes, but there was no difference at 5 minutes or more. There was no racial difference in the pupil dilation response to intracameral lidocaine. Nonpreserved intracameral 1% lidocaine produces immediate pupil dilation in previously undilated phakic patients during trabeculectomy surgery.