Quantitative Analysis of Remineralization of Artificial Carious Lesions with Commercially Available Newer Remineralizing Agents Using SEM-EDX- In Vitro Study

• Published in: Journal of clinical and diagnostic research Vol. 11; no. 4; pp. ZC20 - ZC23
• Main Authors: Shaik, Zaheer Ahmed, Rambabu, Tanikonda, Sajjan, Girija, Varma, Madhu, Satish, Kalyan, Raju, Vijayalakshmi Bhupathi, Ganguru, Sirisha, Ventrapati, Nagalkashmi
• Format: Journal Article
• Language: English
• Published: India JCDR Research and Publications Private Limited 01.04.2017
• Subjects: casein phosphopeptide-amorphous calcium phosphate; icon; vantej; Vantej; Icon; Casein phosphopeptide-amorphous calcium phosphate
• ISSN: 2249-782X; 0973-709X
• DOI: 10.7860/JCDR/2017/22270.9642

The basic principle of remineralization is by advocating a biological or non-invasive approach rather than the surgical approach for early enamel lesions. There are relatively newer products available for remineralization, latest being the resin-infiltration technique, commercially available as Icon. The aim of the study was to evaluate the remineralizing potential of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP), Vantej and Icon by the quantitative evaluation of mineral gain. Seventy eight maxillary premolars were decoronated at Cemento-Enamel Junction (CEJ) and then sectioned mesio-distally using diamond disc into two halves. Mineral content of the sound specimens were recorded using Energy Dispersive X-ray (EDAX) micro-analyser. The samples were then subjected to demineralization by using demineralizing solution. The samples were grouped (n=26) based on the remineralizing agent used, Group 1: Vantej, Group 2: CPP-ACP, Group 3: Icon. After the application of remineralizing agent, the mineral content was measured using EDAX. After remineralization, there was a significant difference between the groups when calcium and phosphorous ratios (Ca:P) were compared, showing greater potential of remineralization for CPP-ACP followed by Vantej and Icon group. CPP-ACP performed better than Vantej and Icon in remineralizing the demineralized enamel.